Aspects of hepatitis C prevalence and characterist

e707004304 · Wysłany: Wto 12:23, 15 Mar 2011

Hepatitis C prevalence and characteristics of areas

. 7%,[link widoczny dla zalogowanych], the former Soviet Union from 1.4 to 4.1; voluntary blood donors or general population,[link widoczny dla zalogowanych], at a small 1.1. India 2.0, China 2.1 Beijing, Taipei 0.95oA. HBV HCV carrier does not like much, but the distribution is quite extensive, combined with Xiao Yi found near to the blood supply is the main source of infection of hepatitis C. 1.2 The main route of transmission of blood, blood products and trace the blood spread. I am Room A case-control study found that cancer risk of hepatitis C infection l Soka be derived. 1.2.1 blood, the blood system of grain and trace the spread of blood Jj ten major route of transmission. Post-transfusion hepatitis (PTH) incidence of about 2 ~ 2O, of 2 to 3.4. Western countries PTH90 to hepatitis C; in my N 70 to HCV. In highly endemic areas, PTH higher incidence of _ 1992, Wo Guo Guan, Hebei Province, 92, 37 Shouxue Zhe Feng PTH occurred, which accounted for 85 Bing Gan,[link widoczny dla zalogowanych], infection rate was 53. In addition, the old foreign reports, the higher the amount of blood transfusion, the higher incidence rate; commercial blood donors servants f the risk of causing more voluntary blood donors with high 5 ~ l0 times. Hemophilia, blood dialysis patients, intravenous drug users, a ltCV positive rate of anti-high blood also suggest the importance of communication. 1.2.2H everyday life, including sexual communication, including contact transmission. } L more before the report in this regard, but research is still little more than standard. Inflammation in the onset JJf open, a higher proportion of hepatitis C: My l2 ~ 24, the United States 2O ~ 44, Japan 45, Europe 9 ~ 18. These patients are likely to foot the result of daily contacts. In addition, a number of scholars from the saliva, and tears were detected HCVRNA, a report found} kl water HCV · 349 · about sexual transmission, the Japanese scholar (1993) with a diagnosis of molecular evolution, JH gene tree analysis of responses were negative attitude. The screening of 50 pairs took a few anti-HCV positive one couple, the couple found that only 4 are both anti-HCV positive one. Type found by PCR in 2 different types of spouse; the other two pairs of couples cut type phase, with the diagnosis of molecular evolution to determine the time ramets strains and found that the spouse of ramet 1 q c made in 45 hours ~ 52 years ago, had been married for 32 years before; No. 2 on the ramets of time has been 30 to 40 years, and only been married for 25 years. 1.2.3 has some information on vertical transmission of HCV bite confirmed by the Maternal and Child (including via the placenta) transmission. Some people think that vertical transmission rate of less than 13, but yet to be further studied. 1.3 susceptible population of HCV are generally susceptible. Gender, ethnic differences and disease related. Health care, feeding people, by the blood of patients, blood disease, dialysis patients; intravenous drug users and homosexuals, prostitutes and other high-risk populations, mainly exposed to opportunities, exposing the way easily infected. Anti-HCV is not a protective antibody, hepatitis C infection has not yet found temporary protective antibodies. 2, the main form of popular features is the dissemination of popular 2.1 can also be outbreaks. Outbreaks often by j: the collective blood products or contaminated injecting equipment caused by the blood. United States (1974), Poland (1982) by a single plasma collection also transfusional hepatitis C outbreak. China 9 October 1985 also occurred in the Gu'an single plasma collection I also lost due to an outbreak of Sapporo, the attack rate of 40.0 (26/65). 2.2 The regional distribution of the disease was a worldwide distribution. Anti-HCV prevalence from a technical perspective, the distribution is not national, but not as good as hepatitis B were very different. The prevalence of the population is 0.5 to 5.0. Prevalence of hepatitis C is more prominent in Japan, and its consequences more severe hepatitis B; HBsAg carrier rate of about 2.0, an anti-HCV prevalence rate was 1.2, but the HBsAg carriers,[link widoczny dla zalogowanych], primary liver cancer (HCC) incidence rate of 0 .25, 『fii anti-HCV positive in a HCC incidence rate of 1.0. 2.3 Characteristics of recipients in patients with good hair. Frequent contact with contaminated blood or infected materials were high, such as medical personnel, laboratory workers, blood disease patients, hemodialysis, drug addicts, blood donors and so on. In addition, anti-HCV-positive mothers of babies born of a sexual relationship who object confusion, hepatitis C RNA content of the patient's family about 9 times the blood; and have played through the saliva rjI also many individual members of such disease. A mushroom in the pathogenesis of hepatitis C Si; Southwest Hospital, Gu Changhai / 26 Bow ,71 -630,038 / Southwest Hospital, Wu J Human Gu Changhai V,[link widoczny dla zalogowanych], wheat basket of the liver deaf one. . Hcv majority of acute hepatitis C mutations develop chronic hepatitis, chronic form of a nozzle on l: .... ... Inflammation rarely relieve itself, and often evolve into cirrhosis, liver cells and even take an HCV RNA viruses, it is prone to mutation. Especially genetic cancer. Group E / NS, the 5 end, the biggest variation. 5-terminal parts of two highly variable