Astragalus adjuvant treatment of children with vir

e707004304

Astragalus adjuvant treatment of children with viral myocarditis 33 Patients

【Abstract】 Objective TCM treatment efficacy of viral myocarditis. Methods 66 patients were randomly divided into two groups and the control group 33 patients in the observation group in the control group based on the use astragalus intravenous infusion, clinical controlled study. The results compared two groups, the observation group total efficiency of 100% in the control group, the total efficiency of 87.9%. The observation group than the control group. Conclusion Astragalus injection adjuvant treatment of viral myocarditis in children is safe and effective, is worthy of clinical application. Key words Myocardial diseases / therapy; viral disease; infants; Astragalus; herbal / therapeutic use children with viral myocarditis There is no specific treatment. Court on the basis of conventional therapy plus adjuvant therapy with astragalus, the effect is obvious, are reported below. 1 Materials and methods 1.1 Clinical data of 2003? 03 ~ 2008? 09 Liaoyang Third People's Hospital pediatric viral myocarditis in children admitted to children with 66 cases, 46 cases were male and and 20 females; aged 18 months to 12 years, mean age (22.0 ± 1.5) months; the shortest duration of 10 d, up to 66 d; average hospital stay was (22.0 ± 3.4) d. No hospital is divided into odd and even numbers by the observation group and 33 patients in control group. Two groups of children in sex, age, disease duration was no significant difference between areas, comparable. 1.2 Western diagnostic criterion-referenced diagnostic criteria for the 6th edition of TCM diagnostic criteria in accordance with the State Administration of Traditional 1994 version of 1.3 treatment of cardiac medications nutrient control group (GIK, fructose, vitamin C), rest and symptomatic treatment. Observation group were treated based on the use astragalus (CTQ Pharmaceutical Co., Ltd., Zhunzi Z33020179, lot number 0211301 and other drugs in 12 batches), ≤ 3 years of age 5 mL, ≤ 7 years of age 10 mL,> 7-year-old added 15 mL 100 mL 10% glucose solution intravenously, day 1 and 2 weeks for a course of treatment 1 to 2 courses. 1.4 statistical analysis using SPSS 10.0 statistical software for statistical analysis, line χ2 test. 2 results 2.1 Clinical criteria of Zhangjiagang, China under the 1987 symposium myocarditis cardiomyopathy standard [4]. (1) markedly effective: Clinical symptoms and signs disappeared, laboratory examination was normal; ECG returned to normal; X-ray chest showed cardiothoracic ratio of about 50%; (2) effective: symptom control or improvement of clinical and laboratory examination was normal or improved; ECG improvement; X-ray chest showed the heart shadow reduced, but the cardiothoracic ratio greater than 50%; (3) invalid: clinical symptoms, signs, laboratory tests, ECG, X-ray inspection does not meet the improved standards. 2.2 markedly observation group compared two groups of 27 cases,[link widoczny dla zalogowanych], accounting for 81.2%, effective in 6 cases, the total efficiency of 100%. Control group, 21 cases markedly, accounting for 63.64%, effective 8 cases, total effective rate 87.9%. The difference between two groups was statistically significant (P <0.01). Table 1. Table 1 astragalus treatment of viral myocarditis in children compared with the control group the efficacy Note: Compared with control group, aχ2 = 4.258, P <0.01. 2.3 two groups of children with adverse reactions were measured before and after treatment of liver and kidney function, electrolytes, and urine will be normal, the results were not found to have abnormal changes. Astragalus treatment of viral myocarditis that security, without any side effects.