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Wysłany: Sob 13:38, 19 Mar 2011 |
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Indicators of metabolic syndrome and its metabolic abnormalities of plasma vWF and NO content
Pulp N0 was significantly higher than the normal control group, but the activity was lower than the control group,[link widoczny dla zalogowanych], which may be caused by insulin resistance vascular bioavailability of NO decreased about I6]. In this study,[link widoczny dla zalogowanych], MD N0 group and MS group were lower than the normal control group, suggesting that abnormal metabolism with MS,[link widoczny dla zalogowanych], when the synthesis of vascular endothelial N0 reduced ability to secrete reduced. But the MD compared with MS,[link widoczny dla zalogowanych], N0 content was no significant difference (P a 0.33), which may be due to MS group than in the MD group had more diabetes (13 cases: 4 cases), and diabetic patients NO in the high,[link widoczny dla zalogowanych], thus affecting the MS group, NO levels, when, after removal of DM patients, MS N0 group and MD group were significantly lower than the control group (P <0.01), and the MS group was significantly lower than MD group (P <o.05). Multiple stepwise regression analysis showed that: the plasma NO levels and TG, body mass index, systolic blood pressure was negatively correlated, suggesting that these factors, the interaction can cause endothelial injury. In the presence of metabolic syndrome, endothelial dysfunction, and MS patients compared with 1,2 abnormal metabolic indexes of endothelial function in patients with more serious injuries. Hence, the control of metabolic syndrome and reduce abnormal metabolic indexes to improve endothelial function and reduce cardiovascular morbidity has an important role. References: [1] XIANGKun-san, JILi-nong, XIANGHong-ding, etal (item Kun III, JI Li-nong, to the red D, et al.) RecommendeddiagnosisstandardtOthemetabolicsyndromebyCDS [J]. ChinJDiabe ,2004,12:156-161. (InChinese) E23WANGHong-man, DENGHua-cong, ZHENGDan, etal (Wang Hong Man, Denghua Cong, Cheng Dan. Etc.). ThechangesofplateletL-arginine/NOsystemininsulinresistancintype2diabetespatients [J]. CHINJENDOCANDMETA ,2002,18:370-371. (InChinese) 1-3] KEDZIORA-KORNATOWSKAK, CZUCZEJK0J, PAWLUKH, eta1. Themarkersofoxidativestressandactivityoftheantioxidantsysteminthebloodofelderlypatientswithessentialarterialhypertension [J]. CellMolBiolLett, 2004,9 (4A) :635-641. [43PANIAGUAOA, BRYANTMB, PANZAJA. Roleofendothelialnitricoxideinshearstress-inducedvasodilationofhumanmicrovasculature: diminishedactivityinhypertensiveandhypdrcholesterolemiepatients [J]. Circulation, 2001,103 (13) :1752-1758. [53BIANNAD, TABERNERDA. Areliablemarkerofendothelialcelldysfunction: doesitexist? [J]. BrJHaematol, 1995,90 (2) :244 - 248. [6] CHIENWY, YANGKD, ENGHL, eta1. Increasedplasmaconcentrationofnitricoxideintype2diabetesbutnotinnondiabeticindividualswithinsulinresistance [J]. DiabetesMetab, 2005,3 l (1) :63-68. [Editor Huang flower]
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