ray ban occhiali Mitomycin C in severe epithelial

43nike9485qt · Wysłany: Śro 16:09, 23 Mar 2011

Mitomycin C in severe epithelial ingrowth after LASIK Application

ASIK more common complications after surgery, with an incidence of about O ~ 20 [1], the reports vary greatly, mainly related to the incidence of epithelial implantation level selection. Significant need for surgical treatment of epithelial implantation rate was 1.7,[link widoczny dla zalogowanych], while the re-operation compared with the initial surgery, a significant increase in the incidence of epithelial implantation. Scholars abroad for treatment of epithelial implantation area excimer laser keratectomy (PTK) and a sponge dipped in alcohol 1O erase the epithelial cells of affected areas to prevent the recurrence of L3], and the group affected by the elimination of surgical District proliferation of epithelial cells, intraoperative use of 0.02 mitomycin C, one case after treatment without recurrence, the treatment success rate was 100%. Mitomycin C (MMC) was isolated from head-like streptomycin, a drug side effects of anti-metabolism drugs, which function by alkylation with the formation of double helix DNA molecules hinge structure and function of DNA damage, inhibition of proliferation of DNA replication,[link widoczny dla zalogowanych], the cells on the proliferation of both the killing effects of period [4], the authors used intraoperative mitomycin C, can inhibit epithelial cell proliferation, effective control of epithelial implantation. MMC can inhibit the growth of various cells, its therapeutic effects and toxicity and route of administration and concentration are closely related, long-term large drops have caused the conjunctiva, sclera, the risk of necrosis [, therefore, the premise of ensuring the efficacy, minimize drug concentration and reduce administration time,[link widoczny dla zalogowanych], the risk to a minimum. I concentration in the intraoperative use of 0.02, and the balance after use with plenty of liquid and rinse thoroughly to minimize the drug residues. Implantation occurred in corneal epithelium exact cause is not clear, possible causes are: epithelial cell ingrowth from the flap edge; the epithelial cell shedding; surgical instruments into the corneal epithelial cell layer and the corneal bed in the wash liquid to the cornea by the into the epithelial cells. As layer of corneal epithelial cell layer of the corneal flap blocking the normal metabolism of glucose from other substances in aqueous, stromal flap necrosis can occur. Corneal epithelial cells release cytokines may also activate the release of fibroblast collagenase enzymes dissolve the protein, resulting in melting of corneal stromal flap. Prevention and treatment of epithelial implantation include: intraoperative epithelial defect to avoid, reduce local anesthetic consumption table, create the corneal flap in the cornea before the wet, check the blade without defects. At first glance there is a large operation such as the epithelial defect, the second eye surgery should not be on the same day, when the occurrence of large intraoperative epithelial defect should be closely observed with regular follow-up, wearing contact lenses; majority of epithelial ingrowth in LASIK 1 month after surgery was diagnosed, so the first 2 weeks of photophobia and irritation may indicate epithelial implantation, so every time the line must be slit lamp microscopy, fluorescein staining, corneal topography examination. As most of the implant is always limited to the epithelial flap margin, usually do not progress, do not affect vision, only when the following conditions need to be addressed: Epithelial implantation of pupil progress to the edge of the lower visual quality; cause corneal stroma and the flap dissolution; causes local uplift caused a significant astigmatism,[link widoczny dla zalogowanych], the corneal flap flap edge or cause irregular fluorescent coloring and foreign body sensation. When these 4 cases there is a appears to be a timely manner. Therefore, implantation of corneal epithelium should be used when drugs such as fluorine conservative treatment of U.S. children and closely observed, Ru healing, you do not need surgery; Ru continue to develop, endangering the vision, You obviously Yiwu sense of sexual advances or for those who Junying Jinkuaishoushu processing, in order to avoid more serious complications.
More articles related to topics：

[link widoczny dla zalogowanych]

mbt zapatos Asthma, chronic bronchitis and allergi

[link widoczny dla zalogowanych]