Structural Characterization of azadirachtin light

ncycgdxhl

,[link widoczny dla zalogowanych]
Structural Characterization of azadirachtin light oxides and biological activity

oro molecular weight can be inferred to be 572, ~ nimbin more than 32 units, for the oxidation products nimbinolide. 2.3.2Isonimbinolide 10.64rllin compound retention time, the 117 / z = 590 ion peak assigned to [M + NH1 +; 111 / z = 595 ion peaks as】【M + Na +; feet = 532.1 ion peaks for the 【M + NH a (a CHo)-co]; m / z = 514.7 ion peak assigned to [M + NH a (a CH: O) - CO - H: 0】 ten; re ~ z - 464.3 ion peaks for the 【M + NH4 one (a CHO) - CO - 2H: O - CH, OH]; m / z = 436.3 ion peaks for the 【M + NH I (a CH: O) a 2CO a 2Ho-CHOH]. Molecular weight can be inferred to be 572, more than 32 units nimbin, as oxidation products isonimbinolide. 2.3.3Salanninolide compound retention time 9.21min, the Shan / z = 646.1 ion peak assigned to [M + NH】 ten; m / z = 651.4 ion peaks as】【M + Na + ; m / z = 629.1 ion peaks for the fM + Hr; re ~ z = 572.0 ion peaks for the 【M + NH-(cHc0O a) a cH, r; m / z = 542.9 ion peak attributed to the 【M + NH - (CH3CO0 -) - CH - CHO]; re ~ z = 524-3 ion peak assigned to [M + NH - (CHcOO a) a cH, a cHO-H0】 ten. Molecular weight can be inferred to be 628, ~,[link widoczny dla zalogowanych], salannin more than 32 units, for the oxidation products salanninolide. 2.3.4Isosalanninolid retention time of 10.99min compounds,; ~ m / z = 646.1 ion peak attributed to the 『M + NH] +; feet / z = 651.4 ion peaks as】【M + Na +; m / z = 601.2 ion peak attributed to the 『M + H - co]; re ~ z = 567.3 ion peaks for the fM + H-CO a 2OH]; m / z = 532.2 ion peaks for the 『M + H-COHr; relative molecular mass can be inferred to be 628, more than salannin 32 units, for the oxidation products isosalanninolid. Crude extracts of azadirachtin after ultraviolet light oxidation, so that such nimbin and salannin furan ring containing low-active compounds with high activity, respectively,[link widoczny dla zalogowanych], into the structure of azadirachtin nimbinolide, isonimbinolide and salanninolide, isosalanninolide, its biological activity by significantly improved. Light oxide Azadirachtin 2.4 Toxicity of diamondback moth in Figure 5 and Figure 6 shows comparison: neem extracts on diamondback moth after photo-oxidation activity increased. Neem crude extract concentration of 400mg / L, the drug after 3,5,7 d,[link widoczny dla zalogowanych], larvae mortality was 50%, 66.67%, 80.00%; by different concentrations of liquid treatment 3,5,7 d larvae in the total amount of crude extract, respectively, according to 390.27,[link widoczny dla zalogowanych],238.89,101.51 mg / L. 8O7O flap above 50 Araliaceae 30 Indian neem Li 201005OJ0015020O25030o35040O450 the concentration of cable / (mg.L) before photooxidation Figure 5 Toxicity of neem diamondback moth recorded concentration / (mg ・ I) Figure 6 photooxidation diamondback moth after the Toxicity of 3 conclusions that nimbin and through photo-oxidation, respectively, into salannin nimbinolide, isonimbinolide and salanninolide, isosalanninolide; but their conversion rate needs to be further explored.