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yxfbbiedtj · Wysłany: Pon 4:22, 07 Mar 2011

NP program second-line treatment of advanced breast cancer

Patients with advanced breast cancer drug,[link widoczny dla zalogowanych], the total effective rate 46.4% (13/2 Cool

, of which CR2 patients (7.1%), PR11 patients (39.3%), with similar results reported at home and abroad. The results in this group still shows that, for different parts of the transfer, the different effect of chemotherapy on the lymph nodes, chest wall, contralateral breast, lung metastases better,[link widoczny dla zalogowanych], but the liver bone [Article ID】 1673-7768 (2008) 06-0877-- 02877 transfer poor results. This result is similar to other reports Yuan acenaphthene. However, a small number of cases in this group remains to be further expanded case studies. The median time to progression 5.2 months, median survival was 10.5 months. Due to short follow-up time, the result remains to be seen. Drug toxicity, primarily bone marrow suppression,[link widoczny dla zalogowanych], primarily to neutropenia, Ⅱ ~ Ⅲ degree reached 85.7%, non-Ⅳ myelosuppression, but after application of G. CsF can recover after treatment, platelet and hemoglobin on relatively small. Vinorelbine and cisplatin, gastrointestinal reactions heavier, the prophylaxis of granisetron and dexamethasone antiemetic, reduce nausea, vomiting extent, Ⅲ degree of gastrointestinal toxicity in 3 cases, the digestive tract without Ⅳ degree reaction. Vinorelbine can lead to phlebitis, but the group due to the use of deep vein catheterization chemotherapy, thus avoiding the occurrence of phlebitis. In summary,[link widoczny dla zalogowanych], we believe that Vinorelbine (Vinorelbine) combined with cisplatin chemotherapy as second-line drug treatment for anthracycline or taxane-resistant advanced breast cancer significantly, and toxicity can be tolerated, and the price is cheap,[link widoczny dla zalogowanych], for a better chemotherapy refractory breast cancer can be considered as the remedy.