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asbryobvrz · Wysłany: Pon 12:30, 21 Mar 2011

EHF efficacy of early prophylactic treatment

(EHF) currently there is no effective treatment. February 1995 一 September 1998 on the basis of our routine treatment for early preventive treatment, more effective, are summarized below. Materials and methods 1.1 Case 1 Select all the 165 patients with epidemic hemorrhagic fever cases were selected in the heat of the patients. Diagnosis of epidemic hemorrhagic fever in 1986,[link widoczny dla zalogowanych], the national uniform standards developed by the Conference, and confirmed by serological detection of specific antibodies. Table randomly divided into treatment group and control group, two groups were the general condition of the degree course and dividing the early set in Table 1. After two general information on admission there was no statistical difference (P> 0O1) Table 1, the general situation of two groups of patients, the course bearing in mind the situation of early dividing method of treatment and observation of 12 patients were admitted to hospital were given infusion, ribavirin intravenous infusion and symptomatic treatment. The treatment group was based on the use of low molecular weight dextran, salvia miltiorrhiza 500ml + 20ml intravenous, day 1; 5GS250ml + dopamine and phentolamine 20mg + 10mg intravenous, day 1, dropping speed is 15 ~ 2O drops / min, speed Urine 20mg bolus, 1 or 2 times a day. Course of 3 to 5 days. Into hypotensive shock and oliguria of those given the appropriate treatment according to each period. After admission blood pressure was measured every 4 hours up to the urine of 1 to 1 every 8 hours, recording daily urine output, each 1 3 check blood, urine and renal function and record the condition changes. 2 Results The results in Table 2. Treatment group, 78 patients with direct access to more of urine poured on, the more of the rate of 92.9. 6 cases of more than 436 * 2 cases of hypotension shock, oliguria of 4 cases. 2 down death, 1 case of existing heart disease,[link widoczny dla zalogowanych], patients died of acute heart failure in oliguria. The urine of more than 1 patient died of intracranial hemorrhage. The average length of stay 12.4 days. Control group, 37 cases of urine directly into the multi-stage, more of the rate of 45.7, more than 44 cases of 13 cases of hypotension shock,[link widoczny dla zalogowanych], oliguria 31 down, hypotension shock and oliguria of 6 cases of 12 down Dead Pest Control in August 1999 Volume 15 No. 8 killed in 2 patients died of refractory shock, 2 patients died of acute heart failure,[link widoczny dla zalogowanych], 7 patients died of acute renal failure,[link widoczny dla zalogowanych], 1 died of polyuria intracranial hemorrhage. The average length of stay 21.5 days. Two groups of cure rate, mortality rate, the more of the rate by a statistically significant difference (P <0.01). The treatment group, no medication during the occurrence of any side effects. Table 2 Comparison of clinical efficacy of the two groups were 3 to discuss the current basic pathogenesis of epidemic hemorrhagic fever recognized is that the virus invades the human body caused by viremia and systemic organs, tissue microvascular endothelial cell damage, the emblem of circulation, and thus hypotension shock. And on this basis of platelet damage, aggregation and dysfunction, DIC formation of multiple organ damage, particularly renal vascular damage caused by renal failure and a series of pathological physiological changes. Based on the above pathogenesis, we heat the prophylactic treatment of low molecular weight dextran can increase plasma colloid osmotic pressure, the expansion of blood volume, maintain blood pressure within normal limits. With compound Danshen a j; starting to play together with lower blood viscosity, blood circulation, improve microcirculation, complement the role of blood volume in the expansion of vasoactive drugs on the basis of phentolamine and dopamine, both play a relieve vascular spasm, expansion of renal artery, increased renal blood flow and effective filtration pressure effect, plus low-dose furosemide can inhibit renal medullary branch of trip-liter Na, CI a reabsorption, Ⅱ renal prostaglandin synthesis, renal blood flow re-distribution, play a diuretic, blood urea nitrogen excretion to reduce kidney damage. The three groups of drugs can block the disease combined with the development, shorten the course and improve the cure rate. Luoyang City Health City Construction riveting , (Luoyang City Health anti-acne station. Luoyang City in October 1986 launched a large area in the city's rodent control activities Patriotic Health Campaign Committee in 1988 was named the provincial standard rodent advanced city. under the correct leadership, mobilize the masses to broad participation, consolidation standard rodent made great success. May 1998 assessment by the provincial Patriotic Sanitation review. The related technical summary report are as follows: a basic situation in Luoyang City, Henan Province western province, is the Yellow River region Iloilo Basin, Henan Province is a large industrial and tourist city. the city's climate with four distinct seasons, with a typical temperate continental climate. city from east to west, north and south narrow, shaped like a belt like, the city area of about 50km, 7O population of more than million. According to the survey, the main urban rat species Rattus norvegicus, Mus musculus and flavipectus. 2 stabilization measures