Analysis of the drug source cerebrolysin reaction

yxfbbiedtj · Wysłany: Pią 19:05, 25 Mar 2011

Analysis of the medicine cerebrolysin SOURCE

Cure diseases such as cerebral dysgenesis. China in recent years only a few reports. The source of their drug response and even more rarely reported, we have since February 9O to 92 years in January, a total of 5 cases of statistics, a brief analysis. A clinical data, general information: This 5 cases, 4 males and 1 female. The youngest were 36 years old, the biggest in 53 years. Application cerebrolysin indications choice: sequelae of traumatic brain injury and memory impairment in 2 cases, right side ineffective activities, high blood pressure and sometimes a fall, after cerebral infarction in 1 case insensitive language clumsy, unresponsive after cerebral thrombosis, indifferent expression , memory impairment in 1 case. Second, the virtual source with the method and its response to clinical medicine: The cerebrolysin 5 ml intramuscularly once a day in 2 cases. 1 case for the first time one hour after intramuscular injection, fever, nausea and headache. Check the body temperature 38.9, blood pressure 1G/12KPa. Another 1 case in the third intramuscular injection two hours after cerebrolysin, headache high blood pressure to 2, l6KPa. 10 ml by adding cerebrolysin 250 ml normal saline drip slowly, 6O ~ 120 分钟 intravenous infusion once a day in 3 patients. 2 sides of them were there in the fifth after intravenous infusion of hot feeling, headache, blood pressure, respectively 2a/15KPa and 20/12KPa, appeared well and there is the side of the limb paralysis in 1 case. Also used in conjunction l case the following morning six days after the sudden dizziness, confusion appears, breathe deep, bilateral and other common ground round pupil, poor response to light, strong items, appear on both sides of pathological reflex, blood pressure To 28/1GKPa. Third, the laboratory tests: white blood cells in the peripheral blood (5.5 ~ 9. Cool

× 10 '/ L between the classification of normal. Complications are exceptions. Fourth, treatment and outcome of 5 patients were disabled cerebrolysin and use anti-inflammatory anti-allergic and symptomatic treatment. 4 commission cured, 1 died of a complication with cerebrolysin hypertensive cerebral hemorrhage. Discussion cerebrolysin standardized by non-protein amino acids and low molecular weight organ-specific properties of liquid water mixed with Taiwan, by the animal protein component in brain tissue obtained by enzymatic hydrolysis process. It sets have all the necessary human and non-essential amino acids and monoamine neurotransmitters and peptide hormones and enzyme precursors, the molecular weight of 1 million or less, through the blood-brain barrier directly into brain cells in the brain from Synthesis and affect the quality of the respiratory chain, can improve brain cell tolerance to hypoxia and hypoxia improved, so that operation of the normalization of glucose disorders, and is widely used in clinical. Although reported in the literature the use of safe, well tolerated in patients with its, but it is after all a kind of biological products, which can lead to drug source reactions, fever in 1 case. It can cause headache, cerebral vasospasm, 5 cases of cerebral vasospasm to the side of a temporary paralysis caused by a blood brain must guillotine. The peripheral vasoconstriction caused by high blood pressure in 4 cases. By intravenous infusion rate is too fast on the Puzzle 2 hot down there. If hormone in the body due to brain half-life time is short, even if there is drug source reaction, withdrawal can be. However, application of the brain due to lack of basic knowledge of living index, intramuscular injection or intravenous infusion during the operation does not bench. Application of the indication control cerebrolysin not accurate enough,[link widoczny dla zalogowanych], the application did not strictly observe the changes in blood pressure after 'in addition to renal insufficiency, allergy, the effect on blood pressure fluctuated shall also be regarded as disabled. Avoid sudden increase in blood pressure serious consequences of intracerebral hemorrhage. L cases of this group, as a lesson.