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yxfbbiedtj · Wysłany: Nie 4:29, 06 Mar 2011

Specification of chronic hepatitis B prevention, diagnosis and treatment of

Of which 15% to 25% of patients eventually died of hepatitis B virus-related diseases. Can be seen, chronic hepatitis B virus infection is a serious health hazard of our people the importance of disease. So far, no effective removal of hepatitis B virus drugs. Therefore, how to regulate the prevention, diagnosis and treatment of chronic hepatitis B virus infection is the majority of clinicians face significant practical issue. Hepatitis B virus infection in natural history and outcome affected by many factors, the treatment of hepatitis B there are also many issues to be resolved. Chronic viral hepatitis as a guide and standardize the diagnosis and treatment, in recent years, some well-known international academic bodies such as the Asia-Pacific Institute of Liver Diseases, the European Institute of Liver Diseases, AASLD have expressed about the treatment of chronic hepatitis B and hepatitis C expert consensus (consensus ) or clinical guidelines (guideline). A long time, clinicians in the prevention and treatment of chronic hepatitis B has accumulated a lot of valuable experience. However, the lack of systematic, standardized clinical research, in particular the lack of drug compliance guidelines for clinical research (GCP) of the large-scale clinical trial results, coupled with the l clinicians often too much emphasis on personal experience and expert opinion, which caused the based on lack of evidence-based medicine is widely used in medicine or therapy clinic. In recent years, driven by the commercial interests of patients with chronic hepatitis using the fear and desire for the psychological healing, in a variety of exaggerated advertising done can not be realized in the commitment to seriously mislead the public and the majority of patients, not only caused them financial burden and psychological damage, but also affects the normal treatment. In order to regulate the prevention of chronic hepatitis B, diagnosis and treatment, December 10, 2005, Chinese Medical Association and the Infectious Disease Branch of liver Branch jointly issued the The guide not only reflects the international prevention of chronic hepatitis B, diagnosis and treatment of the latest achievements, and summarized and absorbed the epidemiology of hepatitis B and l in clinical achievements and experience, the majority of medical workers praise. One of the biggest highlights of the guide is to highlight the evidence-based medicine (evidence-basedmedicine, EBM) thoughts. Evidence-based medicine is not only a clinical research method, but also a model of clinical thinking and practice, that personal experience of clinical decision-making will be present on a particular issue can get the latest medical evidence and the wishes of the patient together . From the perspective of evidence-based medicine, well-designed clinical research, especially randomized controlled clinical trial is the best evidence to guide clinical decision making, rather than too much emphasis on personal experience and authority to experts, more basic research can not simply The results suggest that the clinical. In short, neither in clinical decision-making opinionated, can not repeat what others say, but to make reference to well-designed clinical trials l and to give full consideration to the specific condition and individual patient wishes to make reasonable judgments. The core of the guide include: Hepatitis B is a blood-borne diseases,[link widoczny dla zalogowanych], hepatitis B vaccine is the best preventive measures; lead to disease progression of chronic hepatitis B is the main driving force of high levels of viral replication,[link widoczny dla zalogowanych], antiviral therapy is therefore the most critical treatment; anti-viral treatment should follow a certain indications, interferons and nucleoside (acid) analogues are recognized at home and abroad are effective anti-HBV drug,[link widoczny dla zalogowanych], its indications, dose and treatment should follow a certain specifications. . Finally, it should be noted that we should be fully and correctly understand and master the core spirit of the guidelines, follow the guidelines of the basic principles, but should not blindly believe in and rely on guidelines. In fact, almost all of the guidelines or consensus at home and abroad the preface,[link widoczny dla zalogowanych], have stressed that its main purpose is to help clinicians quickly grasp a particular disease or the latest technology, even if a clear view of the recommendations on behalf of Society, also only clinician decision-making reference. There are many clinical questions lack of reliable evidence, and therefore can not give clear and specific recommendations, or only given experts. In addition, even if the new guidelines or consensus can only reflect the level when finalized, require timely manner with the progress of clinical research l be updated and improved. Current guidelines for the preparation work of magazine invited several young experts to guide prevention and treatment of chronic hepatitis B to interpret the main contents is intended to enable us to know the story behind the development of the guide. They all work in the prevention and treatment of chronic hepatitis B clinical line l, which have more extensive clinical experience; and they often take part in international academic exchanges,[link widoczny dla zalogowanych], and thus on the latest developments at home and abroad and has a good understanding and knowledge. Hope that they can deepen the interpretation of all guidelines on prevention and treatment of chronic hepatitis B understanding and awareness.