Minocycline treatment of acute purulent tonsilliti

e707004304 · Wysłany: Śro 13:48, 16 Mar 2011

Minocycline treatment of acute purulent tonsillitis efficacy

1 day sicker into effect difference or inability to cough up phlegm. Disease and chronic infiltration of adjacent pulmonary segments thick hospital. We are in the original drug treatment based on the use of local irrigation abscess cavity wall, the difference between conservative medical therapy can not wash the treatment, a significant effect. Thick-walled abscess in 2 patients receiving chronic guillotine surgery patients often feel difficult. The reason is that the blood line 2 thereof the local irrigation treatment 13 days after competing in the tender medium to 3O hard drugs into lesions. The final result of the merger and more focus absorption dissipated inside the plot to get an unexpected therapeutic effect, the value of failure, death. . }. . , Have clinical application. . l6 Si Dian twilight dagger, magic, ginger l South bun Die. 111'6. f minocycline treatment efficacy in acute purulent tonsillitis I ~, a Nanjing Medical Imperial College Department of Otorhinolaryngology, First Affiliated Hospital (210029) Cheng Weidong '1994 mine collapse in January ~ June 1995,[link widoczny dla zalogowanych], we adopted legislation in Suzhou Pharmaceutical Co., Ltd. Production of mycophenolate happy acute purulent tonsillitis Walled 5O down. Are as follows. Argue a case selection of clinical data of 93 patients diagnosed according to the literature and case selection criteria [of Clinical Otorhinolaryngology 1991} 5t198], except for pregnant women and breast-feeding children under the age of 12. Patients were randomly divided into two groups: ① treatment group 5O cases, male 29 down and 21 females. Age from 14 to 47 years with an average of 25.3 years. Were down (86.O%) had a history of chronic tonsillitis. ② control group of 43 patients, 27 males and 16 females. Age from 14 to 43 years, mean 26.8 years old. 38 (88.4) had a history of chronic tonsillitis. Second, the drug treatment group method: happy mold cable capsule 100mgf times. Morning and evening services once. Control group; fluoride benzylpenicillin (Ann will cents) oral capsule 500mg / times, three times daily. 5 days treatment in both groups. No other antibiotics and anti-inflammatory drugs. Third, the efficacy evaluation ① cure; symptoms and signs disappeared, peripheral white blood cell count normal. @ Markedly; condition significantly improved,[link widoczny dla zalogowanych], but one indicator does not return to normal. ③ progressive condition has improved. ① no obvious improvement in ineffective refer, or aggravate the situation. ① + ② which is effective. Fourth, the results of the more lined lined treatment group 43 cases, effective in 4 cases, progress in 3 cases, cure rate 86. O. Efficient 94. O%. The control group, the recovery of 27 down. 9 cases were scattered. Progress in 4 cases and 1 case. 65.9% cure rate, a saving rate of 87.8. Two groups, the cure rate P 0.05. Among them, the control group, 2 patients discontinued because of adverse reactions in advance, not for statistics, five,[link widoczny dla zalogowanych], adverse side effects occurred in treatment group 6 cut out (12, O). Of which 3 cases of nausea, dizziness associated with nausea in 2 cases. The abdominal distention in 1 case. Are mild, can complete course of treatment, symptoms disappeared after stopping. Control group, four cases of adverse reactions (9.3%), of which mild rash (2 cases, the early withdrawal as a precautionary measure.) Mild nausea, 2 down, relieve itself. Two groups of adverse events was no significant difference (P> O, 05). Discussion of tonsillitis mostly mixed aerobic and anaerobic infections, deep tissue is a major pathogenic bacteria source. Cable is the second generation mold a happy semi-synthetic derivatives of Ring claims in the strongest antibacterial activity in the tetracycline family of Gram-positive anaerobic bacteria and some negative bacteria, chlamydia, mycoplasma and rickettsia, etc. antibacterial activity than significant. The drug also has a good pharmacokinetic profile, long half-life. High lipophilicity,[link widoczny dla zalogowanych], oral tonsillar tissue after a high concentration of the drug [Drugsl975} 9:251]. Happy mold of claim by the treatment of acute purulent tonsillitis 5O down, a course of clinical cure rate of 86, O, N benzyl penicillin was better than cable. However, the efficiency of the two groups did not seek significant difference. We believe that a happy mold claims a high cure rate with pharmacological and pharmacokinetic profile related. They enjoy,[link widoczny dla zalogowanych], MD, * Jin