Plasma endothelin in children with pneumonia and a

e707004304 · Wysłany: Pią 0:59, 04 Mar 2011

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Plasma endothelin in children with pneumonia and Relationship between arterial oxygen saturation

With the control group, respectively, plasma endothelin levels (82 ± 24) and (75 ± 24) ng / L,[link widoczny dla zalogowanych], the difference was not statistically significant,[link widoczny dla zalogowanych], P> O. 05. Severe pneumonia group,[link widoczny dla zalogowanych], plasma endothelin is (153 ± 44) ng / L compared with the general pneumonia,[link widoczny dla zalogowanych], there was a significant difference, P <0.01. Severe pneumonia complicated by heart failure group and no heart failure group, the plasma endothelin was (211 ± 47) and (142 ± 2 Cool

ng / L, both have very significant difference, P <0.01. 3.2 endothelin pneumonia Su relationship with Tc-Sa0 4O cases of children at the same time as Tc-SaO. Measurement, linear correlation analysis showed that the general level of plasma endothelin pneumonia group (82 ± 24) ng / L and Tc-SaO (0.88 ± 0.02) no correlation (= 25, r = a 0.29, P < O.05). ET severe pneumonia group (153 ± 44) ng / L and Tc-SaO2 (0.78 ± 0.29) was negatively correlated (= 15, r = a 0.9, P <0.05). 4 shows the general discussion of this set of data bearing children pneumonia plasma endothelin levels compared with normal control group no significant difference in plasma endothelin in children with severe pneumonia were significantly increased, with heart failure is particularly significant, the highest up to 3 times the control group, and and positively related to disease severity. Tip general case of pneumonia and no oxygen, not enough to stimulate the synthesis and release of endothelin, heart failure, severe pneumonia, especially associated with the highest concentration of endothelin. Lack of oxygen and carbon dioxide retention due to pulmonary artery spasm toxins and pathogens, stimulating vascular synthesis and release of endothelin, leading to pulmonary hypertension. ET can be seen in severe pneumonia and pulmonary artery spasm pathophysiology of heart failure. The value of the level of endothelin is one of the signs reflect the severity of pneumonia. Therefore, the treatment of pneumonia antagonistic Nei Pisuo has important clinical significance, worthy of further exploration. Tc-SaO is a percutaneous non-invasive, quick to judge the extent of the monitoring tool in children with hypoxia. We were Sa0 children with pneumonia and the analysis of plasma endothelin concentrations, indicating the general Tc-Sa0 pneumonia group was (0.88 ± 0.02) had no obvious respiratory distress and cyanosis, and plasma endothelin concentration and no correlation. In particular, when severe pneumonia complicated by heart failure and persistent Tc-SaO significantly lower (0.78 ± 0.29), lower level of symptoms and degree of heart failure and hypoxia is proportional inversely with plasma endothelin concentrations. Heart failure due to pneumonia in children can be seen Sa0. Decreased endothelin release is to stimulate re-Guangdong Jiangmen Central Hospital, Department of Hematology (529O71) sleep Kettle 1 Introduction / 7 '] / white blood cell acute leukemia (L) observed in the induction chemotherapy most parameters. Whether it changes after induction chemotherapy and efficacy relationships? For which there is an early to judge whether the effect of This paper makes a preliminary study on this. 2 Subjects and methods 2.1 Detection of objects 1994 to 1997, our hospital 4O patients with previously untreated AL patients. All bone marrow cells by morphology and histochemical staining confirm the diagnosis. Three United States and Britain by France (FAB) classification I1], in which undifferentiated acute myeloid leukemia type (M) 9 cases and partially differentiated (Mz) 18 cases of acute monocytic leukemia (M) 5 cases of acute lymphoblastic leukemia I type (I) 6 cases, Ⅱ type (L) 2 cases. 23 males and 17 females, aged from 15 to 58 years old. 2.2 Analysis of blood cells of patients taking the early morning fasting blood 1mL, plus 15 anticoagulant according to potassium 10L. Blood cell analyzer with the hospital CoulterJTIR measured by conventional 4-hour finish. 2.3 The method of tracking patients observed after induction chemotherapy in the review of blood cells every 2 or 3 times, each review of bone marrow after treatment 1. Determine the efficacy of the meeting at Suzhou, revised standards of 1987 1. Effective, including complete remission and partial remission; invalid refers to less than 2 courses of induction chemotherapy followed by partial remission. The number of white blood cells after chemotherapy, changes in the calculation of time to the end of treatment the same day as a starting point. 2.4 The statistical methods used in each group the median level of white blood cell count (range), said; difference between the two groups of measurement data with the rank sum test; count data between groups with xz test. 3 Results The efficacy of AL change in interest rates by the number of white blood cells and the time required a minimum number of WBC after chemotherapy: an effective in 23 cases, WBC 0.8 × 10 / L (O.1 ~ 3.6) × 1O. / L; invalid in 17 cases, WBC 1.1 × 1O / L (0.4 ~ 13.3) × 109 / I. Effective group of white blood cell count was lower than in invalid (P <O.05). And preliminary efficacy of chemotherapy