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Wysłany: Czw 22:33, 17 Mar 2011 |
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2000 to 2002 in 22 hospitals in Nanjing cancer treatment drug analysis of biological agents
. 1678 (2003) 06-0323-03Analysisofbiologicalagentsforcancerusedin22hospitalsofNanjingdistrictbetween2Oo0 ~ 2Oo2SUNChun-yu. FENGLin (e £ AffiliatedHospitalofNangMedicalUniversity, Nang210029, China) in recent years, following cancer surgery, radiotherapy and chemotherapy after three conventional treatment, biological treatment of tumors has been gaining increasing recognition as a new tumor therapy. As immunology, molecular biology and genetic engineering disciplines, such as the rapid development of biological agents for cancer continue to emerge, as the clinicians in cancer chemotherapy and biological therapy provides more choice and improve the effectiveness of drug treatment improved quality of life of cancer patients. In this paper, from 2000 to 2002, Nanjing 22 Hospital, chemotherapy and biological therapy of drug amounts by category statistics,[link widoczny dla zalogowanych], focusing on statistical analysis of 3 years relevant biologics drug use for retrospective understanding of the region of tumor chemotherapy and biological therapy drug use and drug trends. 1 Data sources and methods of this raw data from the 2000 to 2002 in 22 network hospitals in Nanjing, Shanghai and Drug Administration by the Institute of Science and Technology Information Analysis System of Drugs and Medical Information Institute in Jiangsu Province to provide medical information network. 22 Hospital Received: 2003.07.08 Author: SUN Chun-Yu (1957 a), female,[link widoczny dla zalogowanych], Jiangsu irrigation Penan, deputy director of the pharmacist, in hospital pharmacy and management. In 9 tertiary hospitals, secondary hospitals 13. Among them, 14 general hospitals,[link widoczny dla zalogowanych], specialist hospitals eight (including a Cancer Hospital). Sorting by the amount of statistical network of 22 hospitals in Nanjing from 2000 to 2002, various types of cancer chemotherapy drugs and biological treatments the amount, proportion; statistics of 3 years in the amount of medication related to biological agents and the drug amount in the top ten Brand biological agents, data processing, office software used MSExcel2000. 2 Results and analysis 2.1 and biological treatment of anti-tumor drugs in the amount and composition ratio of Table 1 Chemotherapy and biological therapy are divided into eight categories, biological, herbal medication was significantly higher than the amount and structure than other types of drugs , is the main choice of drug clinical treatment. It should be noted that the Since the data sources do not reflect the actual use of these biological agents, it is grouped together with cancer chemotherapy and biological agents in the treatment of: 2.2 the amount of cancer treatment drugs of biological agents and species sorting Table 2 summarizes the various types of cancer treatment associated with biological agents divided into five sub-categories, the statistics show, peptides, proteins of biological agents on the dosage of each year ChineseJournalofBiochemicalPharmaceutics2003 324 years of Biochemical Pharmaceutics Volume 24, 6 liters, while the amount of iRNA agent class is shrinking significantly. Peptides, proteins in a biological agents interferon and interleukin-2 in the 20th century, 80 years for cancer treatment, is the general of Cancer drugs. Thymosin Tel (Zadaxin) In addition to immune stimulation, there are direct anti-virus and anti-tumor effect, present in non-small cell lung cancer, liver cancer and the treatment of melanoma cancer, and so used more, especially small cell lung cancer . Erythropoietin (EPO),[link widoczny dla zalogowanych], granulocyte colony stimulating factor (G-CSF) and granulocyte,[link widoczny dla zalogowanych], macrophage colony stimulating factor (GM-CSF) and other hematopoietic growth factors can improve the chemoradiotherapy after bone marrow suppression, stimulation of blood formation, lower infection rate, for the timely completion of radiotherapy to provide protection. Meanwhile, the application of hematopoietic growth factors makes people not only use of bone marrow, and the use of peripheral blood and cord blood hematopoietic stem cell transplantation, blood diseases from the scope of application expanded to solid tumors, hematopoietic stem cell transplantation promotes collaboration to carry out high-dose chemotherapy. Although the immune RNA derived products can induce in vitro human tumor cell specific cytotoxic effect, but when administered in systemic enzyme susceptible to damage DNA in blood is difficult to markedly, decreasing the amount of current clinical = Table 12000 ~ 2002 Anticancer Drugs on the amount and types of constituent ratio of Table 2, various types of cancer treatment drugs amounts of biological agents (million) and species sorting
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