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yxfbbiedtj · Wysłany: Nie 16:03, 06 Mar 2011

Myelodysplastic syndrome Clinical analysis of 181 cases

2 cases. Stages I by ~ nArbor case of l, I of 2 cases. Ⅲ of 5 down. w 6 cases. A history of coronary artery disease 5 down. 1.2 Turbulent doxorubicin treatment pyran (THP) 40mg / m. The first 1.8 days intravenous; vincristine (VCR) 1.4mg / m, on days 1,8 intravenously; acid splashed Niger Found (pred) 40mg / d orally, through 8d reduced to 30mg, after the new cut; Pingyang mold tangled (B1em) 8mg intravenous infusion of the first 14-15 days, while dexamethasone 5mg intravenous infusion. 15d a course of treatment. Repeat the program at least 2 weeks of intermittent treatment 2. Clinical assessment of systemic symptoms 1-3. Abnormal when the initial treatment disappear. X ray and CT signs of abnormal to normal by the complete remission (CR). Initially measured tumor size was reduced by 5o partial remission (PR), disease progression or tumor diameter reduced Determined to be invalid (NR) 2 Results 2.1 ho therapy group of 14 clinical cases of side CR5. PR7 side. Xun Tu fan code 273500.250012 iNR2 cases, clinical efficacy (CR + PR) 85.7. 2 down orderly had used doxorubicin (ADR) chemotherapy is invalid, the THP treatment. Reached PR,[link widoczny dla zalogowanych], THP and ADR showed no cross-resistance. 2.2 The side effects mainly nausea, vomiting and inhibition of bone marrow function, usually white blood cells after chemotherapy 7 ~ 1Od reached its lowest point, around 10d recovery after chemotherapy stopped. Side effects on the heart is weak,[link widoczny dla zalogowanych], down, in addition to 14 l cases of myocardial strain. 1 do have a history of coronary heart disease patients with myocardial ischemia in ECG was slightly heavier, but I no significant cardiac toxicity. No liver, renal damage and hair loss 3 feeding doxorubicin orderly discussion of topiramate is a derivative of doxorubicin tangled, and has a strong anti-cancer activity, low toxicity, patients tend to tolerate chemotherapy was carried out smoothly so that the literature imidacloprid feeding doxorubicin-based regimen in the treatment of malignant lymphoma orderly and efficient 86.5. topiramate group were feeding the doxorubicin,[link widoczny dla zalogowanych], cyclophosphamide, vincristine, prednisone, mycophenolate tangled Pingyang chemotherapy, clinical efficiency 85.7%,[link widoczny dla zalogowanych], in line with the literature,[link widoczny dla zalogowanych], but also ineffective in 2 cases of patients tangled doxorubicin also made a good effect. doxorubicin treatment of malignant lymphoma orderly despite higher clinical remission rate. But the side effects (especially on the heart .) limited application in the elderly. adjoin feeding doxorubicin cardiac toxicity of less orderly, the group caught with or without coronary heart disease to severe cardiac toxicity. that imidacloprid feeding orderly doxorubicin for the treatment of malignant lymphoid elderly tumor.