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Wysłany: Sob 12:27, 12 Mar 2011
Temat postu: _2884 respectfully of
Advising of the
Problems. 5.1O lost out with the analysis of case records and case reports in the literature without a lost situation. 5.1l clinical multi-center collaborative research literature without a multi-center clinical study mentioned. Discussion of evidence-based medicine in clinical research and clinical practice, an idea,
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, concept and methods. Focus on clinical research and clinical practice strict authenticity and validity of evaluation. Fully reflects the practice of evidence-based medicine is the sole criterion for testing truth, the philosophy. The core is realistic, full monitoring, evaluation and 温故 aftereffect NEW satisfied. It requires an objective, true and rigorous scientific attitude; feasible, credible, reliable testing program; careful, accurate, and wise use of evidence. Practice in medical research. Really understand and use the ideas and methods of evidence-based medicine. Mainly reflected in the following three aspects: ① the best evidence of the acquisition, update and applications. ② practice of scientific research objective, accurate and rigorous. ③ detailed written paper,
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, standardize and reliable. Situation from the literature analysis. According to the international Cochrane Collaboration evidence-based medicine standards. Medical treatment of tinnitus in the clinical trials are still many problems. Mainly in the following aspects: ① TCM diagnosis criteria and standards are not uniform. Most of the literature did not inclusion and exclusion criteria. Therefore,
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, in clinical trial conclusions difficult application. ② evaluation standard and the choice of indicators is not uniform. ◎ samples to determine the number of more casual. Sample size depends on many factors. The correct estimation of sample size to test a direct impact on the rigor and feasibility. ④ method of randomization there is no specific explanation. The principle of random testing is to ensure a balanced line-Africa deal with an important means of factors. Random method should be clearly. Not just simply described as ⑤ group baseline data is not detailed. 51 Most of the literature is not a detailed comparative analysis of baseline data. Difficult to embody the principle of balance. Can not objectively reflect the effects of treatment factors. ⑥ blind utilized. Blind to avoid or reduce the measurement bias, contamination and interference effects. In this study, no one in the literature using the blind method. Makes the conclusions less reliable. ⑦ follow-up,
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, lost, lost cases, and so inadequately described. Difficult to obtain true and reliable results. Affect the credibility of the results. ⑧ the literature is not clear that the statistical methods applied and did not give a specific test statistic value. Can not determine whether the correct statistical method. ⑨ lack of reports of adverse effects. The results show that the literature. Chinese medicine treatment of tinnitus in a small number of clinical trials, RCT. Late start. Coupled with the subjective characteristics of tinnitus. Makes the clinical objective tinnitus testing and efficacy evaluation difficult operation. Increased clinical observation and the difficulty of writing papers. So. Quality literature is also to be further improved. Well known. Clinical medicine is the survival and development. Present. Although traditional Chinese medicine theory can not explain the existing scientific knowledge and its mechanism. However, if after the standard post-RCT studies or rigorous evaluation of clinical practice to prove the authenticity, validity and practicality. In accordance with the concept of evidence-based medicine should recognize its value. So. Extensive use of evidence-based medicine is the development of the pharmaceutical industry provides a good opportunity. Development in the future. Medical treatment of tinnitus in clinical research design need to really understand and implement evidence-based medicine methods and concepts. Increasing the rigor of research design and thesis writing a norm. Truly reflects the traditional Chinese medicine in treatment of tinnitus advantage. So as to promote the clinical practice of Chinese medicine and scientific research level,
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, progress and development. So that the clinical efficacy of Chinese medicine are widely recognized by the medical profession.
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