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Wysłany: Wto 13:53, 22 Mar 2011
Temat postu: tory burch outlet Lower respiratory tract infectio
Lower respiratory tract infection in our hospital and drug resistance of the main pathogens
Train separation (separation method is to manually add automation equipment: ATB bacterial identification and susceptibility tester) a pathogen 732, the positive rate of 3O. 55, Gram-negative bacteria pathogens, accounting 6O. 11, 21.45, followed by fungi and Gram-positive cocci 15.16, Table 1. Table 1 732 656 * constitute the major pathogens of Guangxi Medical University 2006Aug; 23 (4) 2.2 2.2.1 pathogen resistance in the major resistance of Gram-negative bacteria, in Table 2. Table 2 mainly Gram-negative bacteria resistant to commonly used antimicrobial agents rate () 2.2.2 mainly Gram-positive bacteria resistance. Table 3. Table 3 mainly Gram-positive bacteria on antibiotic resistance rates () 2.2.3 fungal drug resistance, see Table 4. Table 4 fungi resistant to commonly used antifungal agents rates () 3 to discuss national data reported hospital-acquired pneumonia bacteria to gram-negative bacilli is still showing the state of affairs, the first set of data, in addition to yeast, the respective listed in Section 2 to 5 bits are Gram-negative bacteria: Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter; Gram-positive cocci to B streptococcus, hemolytic Staphylococcus based. It should be noted that in recent years the literature has been reported that Acinetobacter significant upward trend, up 31.4 ridicule, Acinetobacter in this group ranked five percentage gap between the trend and reported that some, but should arouse our attention With the new broad-spectrum antimicrobial agents continue to emerge and extensive use of previously weak pathogenic bacteria that cause infection and gradually increased. In the large selection pressure of antibiotics, virulence and drug resistance of less than the survival of bacteria in the song more,
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, when these bacteria become the dominant bacteria, the resistant and susceptible 'to be more difficult _】]. Fungal infections, the most vulnerable to the predilection sites for the lower respiratory tract,
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, so the next in a substantial proportion of respiratory tract infection, mainly by yeast-based, the separation rates have gradually increased the trend 『{], this set of data consistent with national coverage . Analyze the reasons and underlying diseases of certain infections with corticosteroids, immunosuppressive agents, radiotherapy and other treatment, so that decreased immunity, but not with an increase in a variety of diagnostic and therapeutic invasive procedures have some relevance, the widespread use of antibiotics, and even abuse is caused by fungal infection is another important factor. From the bacterial resistance of view, Table 2 shows the strongest effect of imipenem on gram-negative bacteria, followed by amikacin, imipenem-resistant Pseudomonas aeruginosa to the lowest; Klebsiella pneumoniae coli to penicillin, cephalosporins were high resistance, MDR Acinetobacter common, but sensitive to imipenem, basically consistent with the reported 『5]. Table 3 shows that Gram-positive bacteria are highly sensitive to vancomycin. Staphylococcus haemolyticus resistant to penicillin rate> 9O. Erythromycin, second-generation quinolone resistance rate> 8O,
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, which may control the use of clinical vancomycin. Penicillin and erythromycin as first-line drugs, the resistance rate. The third line drugs as vancomycin resistance rate of its very low, suggesting that attention must be the rational use of antimicrobial agents and collaborative management of sensitive drugs. Vancomycin is the treatment of MRSA is currently the drug of choice, but abroad, has been Staphylococcus aureus resistant to vancomycin, the report appears 『】] should pay attention to. Irrational use of antimicrobial drugs is causing lower respiratory tract infection within the hospital an important factor. Therefore, the proposed emphasis on pathogens check them to do sputum bacterial culture and sensitivity test. Bacteria room should be closely linked with the clinical and timely feedback and medication based on susceptibility results, the correct medication to master the principles of empirical, non-abuse of antibiotics and reduce drug prevention,
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, strengthen disinfection and isolation measures to prevent the spread of resistant bacteria in hospital cross.
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