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Wysłany: Pią 9:34, 04 Mar 2011 Temat postu: 复方鳖甲软 |
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复方鳖甲软肝方对自发性高血压大鼠心肌纤维化的抑制作用
.LiuZ『_quan.DepartmentofPhysiology,MedicalCollegeoftheChinesePeople’sArmedPoliceForces,Tianjin300162,ChinaDoiEr-qing,DepartmentofTraditionalChineseMedicine,AffiliatedHospi-tal,MedicalCollegeoftheChinesePeople’sArmedPoliceForces。Tianjin300162,ChinaTongChang-qing★,Male,ManchuNationality。Bomin1952inLiaoyuanCity,JilinProvince,China,GraduatedfromInnerMongoliaMedicalCollegein1985.Master,Profe∞or.Researchdirection:cardiovescularphysiologyande蠢rcisephysiology.changqingteng2003@yahoo.tom.cnTelephone:+86-22-6o578084Supportedby:ScientificResearchFoundationofMedicalCollegeoftheChinesePeople’sArmedPoliceForces.No.WY2002-8·Received:2004一O7—01Aeeepted:2004一O8—28And:ToinvestigatetheeffectofChineseherbsontheregressionofmy—ocardialhypertrophy,andstudythechangesofendothelin(ET)andcalci-toningene—relatedpeptide(CCRP).METHODS:Wistarratsweredividedintohypertensiongroup(n=48)controlgroup(n=32),thenthehypertensiongroupwassubdividedintohy—pertensiongroupI(n=12),hypertensiongroupII(n=12),Chineseherbtreatedgroup(n=12)andcaptopriltreatedgroup(n=12),andthecontrolgroupwassubdividedintocontrolgroupI(n=20)andcontrolgroupII(n=12).11Ieindexesweredetectedatthe4weekinthehypertensiongroupIandcontrolgroupI。butatthe16weekintheChineseherbtreatedgroupandcaptopriltreatedgroup.Theratmodelsofmyocardialhypertrophywerereconstructedbycoarctationofabdominalaorta.CGRPandETweremeasuredwithradioimmunoaesay.RESULTS:ThemeanartetiMpressureinthehypertensiongroupII【(86.18±19.95)ⅫHg]washigh=thanthatinthehypertensiongroupI
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