 Wysłany: Nie 12:18, 13 Mar 2011 Temat postu: Well cough and cold tablets of paracetamol prime a |
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| Well cough and cold tablets of paracetamol prime and more willing to determination of ether
200mg, more willing to ether 60mg, home 200mL volumetric flask, add the mobile phase A dissolved and diluted to the mark, shake, precise amount of l0, 20,3 O, 40,50 mL split 100mL volumetric flask,adidas scarpe, diluted to use the same solvent scale, shake determination under way by the determination of a concentration as abscissa and peak area for the vertical axis, acetaminophen, and more willing to ether of linear equations in Table 1: Table 1, acetaminophen,UGG boots Italia, and more willing to ether linear relationship (n = 5) Tab. 1Linearcorrelationofprarcetamolandguaiphenesin good linear relationship between the old ceramic components test accurately weighed 2.4 Recovery of paracetamol reference substance about 20,ghd outlet,30,40 mg of the two, split in 100mL flask,keen shoes sale, and the other more accurately weighed Gan ether 7, lO , 13mg each in duplicate, were added to the 100mL flask, each flask add blank materials 8mg, phenylephrine hydrochloride and chlorpheniramine maleate in a mixed solution (weighed phenylephrine hydrochloride 5mg, Chlorpheniramine Maleate 2mg, dissolved in mobile phase A and dilute to 100mL) 10mL ~ dissolved in mobile phase A and dilute to volume, shaken, filtered, the filtrate obtained as a continued recovery of the solution, according to assay methods under measured to calculate recovery. Of the B 1 Ye Xiangyang, et al: Happiness cough and cold tablets of paracetamol prime and more willing to determination of acyl ether 6 were average recovery of phenol 100.3%, RSD = 0.8%; more willing to ether 6 copies of the average recovery 99.5%, RSD = 0.9% 2.5 Recovery test reproducibility test obtained under which a solution of 6 successive injections of acetaminophen RSD = 0.3%, more Gan ether RSD = 0.6%, good reproducibility. 2.6 Test Stability Test 6 were obtained recovery solution, place 24h after the determination of the basic stability of the results in Table 2. Table 2 Stability Test Results Tab. 2Resultsofstabilitytests24oo227245181136514023548952476756346928782411584245061636721493545062471690446654272.7 method of determination according to the results of three batches of samples in Table 3.3 discussed and adopted a series of experiments show that this method can effectively separate the components shown in Figure 1, one can detect two components of which , the operation simple and fast, accurate and reliable for its quality control. Table 3 Determination results of samples of Tab. 3Determinationresultsofsamples1 acetaminophen more willing to ether Figure 2 1HPLC chromatogram Fig. 1HlPLCchromatogram |
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