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bcl-6 gene polymorphism and non- coding region of structural protein expression and relationship between transitional cell carcinoma
Organization of bc1.6 protein positive rates were 68% , 46%, significantly higher than transitional cell carcinoma of grade Ⅲ . The staining results with the literature [ 3,Christian Louboutin Ireland,4] and squamous cell tumors in the study were similar to bcl envisaged a 6 protein in transitional cell differentiation may play an important role . Study also found that , bc1.6 protein in transitional cell carcinoma of the over- expression of 5 UTR -1 mutation is not associated parts of the structure , but in 47 cases of transitional cell carcinoma showed strong positive cytoplasmic 5 cases Specimens, there were a 6 bcl -1 gene in non- coding region polymorphisms of parts of the structure ,mbt shoes outlet, so that this region mutation or deletion of genetic changes such as abnormal expression may be involved in the process , but has yet to be confirmed in further studies . In short , bc1.6 genetic changes and protein overexpression in urinary tract malignancy histological grade and differentiation play an important role. [
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