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Wysłany: Pon 12:12, 17 Sty 2011 |
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Bacterial prostatitis and drug resistance of prostate flora survey spectrum
Almost 100%; In contrast, for other drugs such as vancomycin, nitrofurantoin, morpholine ah ketones almost all sensitive. Sensitive to rifampicin slightly lower rate of addition of Enterococcus faecalis,[link widoczny dla zalogowanych], almost all above 80%, Streptococcus agalactiae and enterococci as much as 100% of the hen; rifampicin are semi-synthetic broad-spectrum fungicide, and depending on DNA and RNA polymerase subunit 13, a solid combination, which inhibit bacterial synthesis of RNA, DNA connection to prevent the enzyme and block the RNA transcription process, inhibit bacterial growth and reproduction, with a broad spectrum antibacterial, antifungal and strong, in vivo absorption and distribution good barrier characteristics through the prostate, is a promising treatment for bacterial prostatitis drug. Staphylococcus aureus resistant to oxacillin was 25%, while Staphylococcus epidermidis and Staphylococcus haemolyticus oxacillin resistance rate of 79.2%, respectively, and 74%, according to NCCLS susceptibility rules, oxacillin-resistant Staphylococcus all B-lactams, including inhibitor containing the compound preparation and carbapenems clinical drug treatment fails, it is appropriate to use clinical treatment. Rifampicin, oxacillin resistant Staphylococcus aureus in vitro activity is higher, but since the majority of oxacillin-resistant Staphylococcus aureus with rifampicin on the single-drug resistance rapidly, it is rarely alone. In terms of Staphylococcus epidermidis, coagulase-negative staphylococci to oxacillin and its criteria for judging the existence of mecA gene-related. For oxacillin-sensitive bacteria, whether by injection or oral cephalosporin, B a lactam / B lactamase inhibitor mixture and carbapenems drugs should be based on routine experiments to determine the results of standard reports, but if strains MICs ≥ 4g/ml,[link widoczny dla zalogowanych], even if the mecA gene negative or do not produce penicillin-binding protein, should also report the strains resistant to oxacillin. Analysis shows that the incidence of bacterial prostatitis and Gram-positive cocci, especially coagulase negative staphylococci are closely related to the suspected bacterial prostatitis prostatic fluid should be done as soon as possible bacterial culture, bacterial culture and sensitivity test based on the results of use of drug-sensitive choose to pass through the prostate capsule to achieve effective therapeutic concentrations within the prostate drug, and consider the joint application of antibiotics,[link widoczny dla zalogowanych], reasonable enough, enough to make good use of antibiotic treatment to prevent drug resistant strains and reduce drug resistance. 【
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