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ORANGE EKSTRAKLASA
Dołączył: 26 Paź 2010
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Wysłany: Nie 23:31, 20 Mar 2011 |
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Aloperine on immune cell function
edinhibitoryeffectonmacrophages. resultinginreductionofIL a 1production. Ahadasimilareffecto13IL - 2productioninmicespleencells. KeywordsAIoperineIL a】 IL-2Lymphocyteproliferation nitroglycerin on hemodynamics in elderly patients with liver cirrhosis and its clinical significance 'of Jilin Province People's Hospital, linked Guo Xiao Qin Xiao-Ling Yang Ad joint '1 in data and methods also detect objects ① outpatient and hospitalized elderly patients with liver cirrhosis 36 cases. Were male, mean age 62 ± 7-5 years. After a detailed examination (imaging, blood, etc.), according to Child - pugh classification factors. Divided into A, B, C three cases of the l2, @ instruments and Methods ATLu-g color Doppler ultrasonography. Convex probe, a frequency of 3.5MHz. Before the test subjects in the 3d, disable all the hemodynamic effects of drugs and blood transfusion, transfusion before the test blank t fishy 8 ~ 12h. Each was the first detection of portal vein blood flow index as the basis of control, including the diameter (Dpv), blood flow velocity (Vpv), blood flow (Fpv) were measured simultaneously mean arterial blood pressure (MBp) and heart rate (HR). NG0-5mg and then to patients after sublingual 10,[link widoczny dla zalogowanych],2 O and 30mint with position, repeat the test three times with the site, take the mean recorded. 2 Results ① sublingual NG0.5mg, the levels of patients had mild Dpv expansion, but no significant difference before treatment (body> O.05). A,[link widoczny dla zalogowanych], B level when the patient 1O and 20rnin Dpv decreased,[link widoczny dla zalogowanych], Fpv significantly reduced, with significant difference before treatment (P O-05). C-class patients ( P> O.05) were not significantly different. ② within the sublingual NG30rain. Fpv decreased. A level was 16.1 (dead 0.05) @ f1 veins within 30min after treatment the average blood flow down the trunk l0.92,[link widoczny dla zalogowanych], mean arterial blood pressure decreased by 15.86 was statistically significant positive linear correlation analysis correlation (y-o.77), average heart rate increased l7.63, with significant difference before treatment (P <o.001). 3 discussed the current use of medication to reduce the portal ① resistance and reduce f] vein blood flow, to control variceal upper gastrointestinal bleeding has attracted wide attention and received good results. The team observed that pulse pressure of older patients with cirrhosis of the liver provides sublingual NG0.5mg, 30rain Dpv seen in mild expansion, Vpv obvious reduced, Fpv significantly reduced. but its role in the disease varies with the intensity of light saddle condition A, B level clearly, C-class is not obvious. NG sublingual role in sustainable 30m_m, but the peak short-lived. @ This group shows including After 30rain the Fpv of NG decreased, MBp down, and both were positively correlated, while HR increased. This is consistent with the literature. that act on vascular smooth muscle wall of the NG special nitrate receptor, causing vascular relaxation. so f] and portal vein system, the expansion side of the body vessel, reducing resistance and reduce portal pressure. same vein dilation, venous stasis. reduce the heart before and after the load, reduced cardiac output is reduced portal blood Wei, one of the reasons. This also shows that as the arterial pressure reduced by baroreceptor stimulation, reflex sympathetic activity from the bow l, Hee-mediated visceral reaction of the blood arm, the portal blood flow reduction, n pulse pressure is reduced. The C-critically ill patients in this group because it usually has in compensatory sympathetic excited state, after application of NG or NG can not increase its activity decrease caused by small artery pressure, visceral vasoconstrictor responses mediated also reported weak. So for patients with advanced liver cirrhosis with severe reduction NG hepatic blood flow, reducing the role of portal pressure is not ideal. @ This group of elderly patients to have uneven hardening of the dynamic hot, coronary heart disease expression. We apply NG can effectively reduce the portal pressure, but also avoid the liver Wei reduction in blood increased the role of liver damage. So NG is an ideal lower f] pulse pressure, control of bleeding esophageal varices because of its role of vasodilator drugs to ask short, it is most suitable for elderly liver upper gastrointestinal bleeding in patients with hardening of the provisional application. * Second Hospital of Changchun City (
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