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yxfbbiedtj · Wysłany: Wto 16:01, 22 Mar 2011

Amitriptyline in the treatment of diabetic peripheral neuropathy clinical observation

5, no significant difference, there is comparability. 1.2 Treatment with amitriptyline in the treatment group stab control chip 5-25mg / O ~. 2-3 times a day, can be gradually to 150 - 250mg / 1 ~ t. The control group VitP ~ lOOmg and vitBa2500 ~ g intramuscularly,[link widoczny dla zalogowanych], 1 day, both at 15 days for treatment. Method of treatment of diabetes including insulin therapy and hypoglycemic agents Ill services. Fasting blood glucose before and after treatment,[link widoczny dla zalogowanych], blood pressure,[link widoczny dla zalogowanych], AIT, BuN, Cr and blood and urine routine clinical examination. 2 results of the treatment group than in the control group,[link widoczny dla zalogowanych], 21 in physical pain, numbness,[link widoczny dla zalogowanych], cold symptoms significantly improved (P <0.O1), Table 2. Table 2, the two sister-like turn for the better after treatment, Zhu cases compared with the control * P <OOl2.2 side effects of drowsiness and clinical examination in 4 cases the treatment group (10%), dysuria in 6 cases (15%), blurred vision 3 feeding (7. 5%), a dose-dependent tendencies. Clinical examination in the normal range of blood pressure changes, into the Medical College 2o01 on Ning L5 No. 4 (Joust. F Ⅺ A pair of ngMedG. Le) increased slightly in 8 cases (20%) BuN, Cr, blood, urine, normal fasting glucose, or no worse. 3 Discussion of diabetic peripheral neuropathy is mainly due to nerve tissue metabolism and microvascular disease, so that segmental demyelination of nerve fibers, Schwann cell damage and varying degrees of axonal damage, the main symptoms are gloves, socks like sensory dysfunction , were pain, numbness, cold and so on. Amitriptyline by stabilizing the cell membrane, so that nerve fibers myelin, axonal damage reduced pain caused by material on the role of a certain block; Amitriptyline absorption were higher in the thalamus and other parts of the role of the hypothalamus in the network structure of a system, sensory conduction block to improve pathological numbness; anticholinergic effects of amitriptyline, causing skin temperature increase and improve hair cool. After a short-term clinical observation, I believe that amitriptyline can significantly improve glucose week of illness kitchen neuropathy pain, numbness, cold symptoms, diabetic peripheral neuropathy is an effective treatment, worthy of clinical application. c2001-04-18 Received) microwave treatment of the laryngoscope 14 cases Wangxian Hong epiglottic cyst. Xieying Li (Nanjing Medical College Hospital into the Department of Otolaryngology. Tide north into Ning 4371 ~) in the Kids in Classification: R767.5 Document code: B Article ID: lOo8 a o635l20o1) 04-0277-0l epiglottic cyst in the direct laryngoscopy completely removed under the dissection, the operation inconvenience. In order to find a simple way, our department from l995 to 2000, on May l2 months in 14 cases of patients with recurrent epiglottic cyst suspension laryngoscopy approach to microwave ablation treatment observation, drums fruit satisfaction, report summarized as follows. General information on the clinical data I I1 l4 cases, 8 males and 6 females, aged 25-28 years; treatment time of 3 months to 4 years. Symptoms are: I4 cases of foreign body sensation, hoarseness in 5 cases, 8 cases of throat, cough u cases. Indirect laryngoscopy showed a cyst under the limitations of a smooth bulge visible, white or light yellow, edges neatly, if no significant border congestion. 14 cases of cysts are located in the epiglottis, tongue, 1O cases in the middle wall of the epiglottis, and 4 located in the valley of the epiglottis. Cyst was confirmed by pathology in all cases, 4 cases of cyst dissection was made, with the recurrence :2-5 years. I. 2 Methods All patients were intravenous anesthesia, laryngeal line with 1% tetracaine topical anesthesia 3-5 times. Laryngoscope exposed throat. Microwave power adjusted to 35 to 45 watts, with a monopole radiation head of the cysts more radiation, selected according to cyst size 4 to 6 points, acupuncture points organized white, until the organization flat so far. 2 Results After treatment, all 7 of hormone treatment with antibiotics + a l1) days, while topical gentamicin and dexamethasone treatment of aerosol inhalation, l see the epiglottis flat weeks after referral, pseudomembranous gradually fall off, new normal mucosa. Obstruction and foreign body sensation disappeared, recovered, after June 1 3-year follow-up, smooth the surface of the epiglottis, the normal mucous membrane color, no discomfort, no disease recurrence. 3 Department of discussion most of the epiglottic cyst duct obstruction caused by mucus from mucus accumulation. 14 cases belong to this article, few reported as epidermoid cysts, this absence of such cases. Epiglottic cyst is not very clear cause of the current may be related to inflammation or mechanical factors in the mucous glands blocked Erzhi mucus retention related. Previous surgical dissection is complete resection of the cyst. But in this exploration of the cavity and in the case of the narrow operative field completely stripped down cyst is more difficult, and easy to relapse. Paper had done in 4 cases of recurrence after surgical stripping to come for treatment. Microwave treatment, easy operation, less damage, the patient less pain, and simple, easy and worth promoting. (2001-09-03 Received}