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ORANGE EKSTRAKLASA
Dołączył: 26 Paź 2010
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Wysłany: Pią 3:24, 25 Mar 2011 |
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Insulin glargine combined with Glipizide GITS treatment of type 2 diabetes
Before the knee function score by Ly-sholm ...: 22 ~ 76 (48.5 ± 6.2) points. Cases of meniscus injury in 41 cases, 29 cases of discoid meniscus , synovial plica syndrome in 15 cases ; 14 patients with osteoarthritis of the patellofemoral joint disease in 11 cases, knee [2] RiddleMC, RosenstockJ, GerichJ. InsulinGlargine4002StudyInvestigators. Thetreat-to-targettrim: randomizedadditionofglarsineorhumanNPHinsulintooraltherapyoftype2diabeticpatients [J]. DiabetesCare, 2003,[link widoczny dla zalogowanych],26 (11) :3080-6. [3] HOE901/2004StudyInvestigatorsGroup. Safetyandefficacyofinsulinglargine (HOE901) versusNPHinsulinincombinationwithoraltreatmentintype2diabeticpatients [J]. DiabetMed, 2003,[link widoczny dla zalogowanych], (20) :545-51. StudyontheefficacyandsafetyofInsulinGlarginecombined,). rithGlipizideGITSinthetreatmentoftype2diabetesmellitusPanTianrong,[link widoczny dla zalogowanych], WangChangjiang, HeYong, etal (DeptofEndocrinology, TheFirstAffiliatedHospitalofAnhuiMedicalUniversity,[link widoczny dla zalogowanych], Hefei230022) AbstractObjectiveTocomparethebloodglucoselevelandassociatedhypoglycemiarisksbetweenusinginsulinGlargineorhumanNPHbothcombinedwithGlipizideGITSintheTreatmentofType2diabeticpatients. MethodsSixtycaseswithinadequateglycemiacontrolinducedbysulfonylureaand / orotheroralagentswererandomizedintotwogroups (1:1). Thebloodglucoselevelandincidenceofhypoglycemiawereobserved. ThedailydosagesofGlargineandNPHwererecorded. ResultsMeanofFBGanddailyglucoseprofileweresimilartothatinthe2groups, buttheincidenceofhypoglycemiaatnightintheGlarginegroupwassignificantlylowerthanthatintheNPHgroup (P <0.05). ConclusionBedtimeinjectionofGlarginecombinedwithGlipizideGITSCanachievebloodglucosecontroltargetandbesaferthanusingNPH. MeSHinsulin / therapeuticuse; glipizide / therapeuticuse; diatetesmellitus, type2/drugtherapy
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