Bronchiolar - alveolar cell carcinoma of the effic

ncycgdxhl · Wysłany: Wto 0:07, 08 Mar 2011

Bronchiolar - alveolar cell carcinoma of the Efficacy of 57 surgical

Were divided into two groups: patients with primary lung cancer group, including 34 cases of squamous cell carcinoma, adenocarcinoma ∞ down, small cell undifferentiated carcinoma 6 down, 2 down too much cell carcinoma; pulmonary benign lesions in 9 cases, 6 cases of chronic inflammation , tuberculosis,[link widoczny dla zalogowanych], 2 down, one case of inflammatory pseudotumor. Monoclonal antibody, type, molecular weight 9.5 × (Preparation of the CAS Shanghai Institute of Cell Biology.) Imaging instrument is ApexSP-6 single-photon emission computed tomography (Sr ~ CT, United States, El ~ ini companies). Single probe low-energy high-resolution machine configuration parallel to the hole collimators. Will hbI. C-1 fragment obtained by trypsin degradation, use of vitamin c as a reducing agent, to snail tags, more than 90%. Each patient intravenous dexamethasone to avoid orange 1O;, and then injected with Rb fragment labeled I ~ -1 25 ~ 35 Ⅱ (925 ~ 1295) t, mq, 1 Ⅱ: 37 Ⅷ q), 3 ~ 24h underwent lung scintigraphy . Raw data normalized by the computer, re-transverse, coronal, sagittal three-dimensional CT images. Lung field of lung diseases, such as within the local uptake of radioactive anomalies, higher than the corresponding parts of the sub-normal side is positive, no radiological abnormalities of lung lesion uptake was negative. Sense of interest to further define areas (R0I), as I set the corresponding parts of the tumor and the radioactive count of the contralateral tumors were calculated, non-tumor radioactivity ratio (stare). Results of lung imaging in the intravenous injection of radioimmunoassay spider TM (If.1IgM fragment was the best image quality 6h imaging. 62 cases with primary lung cancer subjects as the RII-positive, and five 164); Health Science Foundation of China (94-1-151) Author: 20D Qin 2, Zhongshan Hospital, Shanghai Medical University, Thoracic Surgery (once bright, Xu Songtao), Department of Nuclear Medicine (Chenxue Fen, Zhao Shu-win); Biology, Shanghai Institute of Chinese Academy of Medical Sciences (Springs driving,[link widoczny dla zalogowanych], Ge Xirui) Boke weak and negative in 9 cases; nine cases of benign lung lesions PdI positive in 2 cases, negative belly in 5 cases. The chi-square test = 14.576, dead 1.2: Imaging of lung cancer false negative in 9 cases of adenocarcinoma in 4 cases, squamous cell carcinoma in 3 cases, small cell carcinoma in 2 cases. benign lung imaging in 2 cases were false positive chronic inflammation, preoperative cr checks are also misdiagnosed as lung cancer: patients with primary lung cancer & NT is 1.0-21,[link widoczny dla zalogowanych], the average 1. 353 ± 0209; 9 benign lung lesions, T,[link widoczny dla zalogowanych], NT 10-14, an average of 1078 ± 0.139o handled by the statistical test, = 10160,[link widoczny dla zalogowanych], P <0. (El. this group the sensitivity of lung cancer cases and 85 RII .5%, specificity was 77.8%, total diagnostic rate of 4.5% sundial. The diagnostic sensitivity of cr g70%, specificity 66.7%, the total rate of 84.1% diagnostic character sets. small number of cases in this group also carried out Ecr chest computed tomography, compared with planar imaging, higher sensitivity and accuracy. Radioimmunoimaging of lung cancer is a discussion of anti-cancer antibody fragment specific guidance or means of delivery, After the injection of radionuclide labeled the human body, its localization in tumor tissue, nuclear medicine imaging equipment used for in vitro detection of tumor edge location of a medical diagnostic technology. It is based on anti-lung cancer-associated antigen-specific antibody and end station principle, can make a diagnosis of lung cancer: LC.1 against epitopes in lung adenocarcinoma and small cell carcinoma of the expression of a certain level, but its molecular weight, less able to shoot through the organization, in the bloodstream slow. trypsin degradation as I flail their fragments, the molecular weight of smaller tissues in the body's ability to enhance penetration, rapid transmission in the bloodstream, the immune activity, quickly gathered at the tumor site. with the radioactive element edge ‰ R labeled antibody line RII, is simple, easy to control pollution, radiochemical purity, product stability, the image is clear and easy to kit form and so on. we ‰ McAb labeled anti-human lung fragments for radioimmunotherapy of lung cancer was Like, the sensitivity, specificity and accuracy is still satisfactory. tomography applications, makes the image clearer, to improve the sensitivity and accuracy of diagnosis of lung cancer. RII and cr, respectively, from the structural changes in two different angles to diagnose cancer, which concluded with a complementary combination of both applications can improve the diagnostic accuracy of lung cancer. If RII and cr to develop image fusion technology, but also functional changes to improve the anatomical resolution of lung cancer rate, and pull help to improve the accuracy of diagnosis of lung cancer.