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yxfbbiedtj · Wysłany: Czw 15:39, 17 Mar 2011

Amoxicillin drug eruption caused 34 cases

Erythema type of investigation platelets, blood coagulation time were within normal limits. 3 down 34 down in the total number of leukocytes increased> lO × 109 / L, total 8.82; 4 down does not increase the total number of white blood cells, and eosinophils increased (O.06 ~ 0.0 Cool

, accounting for 1】 76.3 Treatment and prognosis after diagnosis, immediately stop using the hydroxyl Yi benzyl penicillin, the symptoms of mild to give antihistamines ship, calcium and vitamin c, the symptoms are relatively heavy given corticosteroids, and 34 all fall cure the vast majority in 3 to 5 days after treatment rash gradually subsided after 1 week recovery. 1 down and 1 case of purpura type erythema multiforme after treatment for 2 weeks before the rash subsided. 4 OH N benzylpenicillin discussed as a 13 semi-synthetic penicillin, ampicillin,[link widoczny dla zalogowanych], Department of nitrogen derivatives, broad spectrum antimicrobial. Department of strains and strong, and do not need to do skin test, easy to take, has been widely used in clinical version of the British Pharmacopoeia 1988 and the United States Pharmacopoeia (22 Edition) provides not proud of allergy tests,[link widoczny dla zalogowanych], but in the actual process of taking the drug-induced skin irritation reaction is more common,[link widoczny dla zalogowanych], the incidence rate of 2 such as severe erythema multiforme, bullous skin orange solution type, also saw a beam of adverse visceral system damage, indicating that hydroxyl nitrogen benzylpenicillin is relatively safe because there are two antibiotics, the incidence of hard drug eruption, and this paper cases involved a claim down has used Anbianqingmei allergies, a do have a history of allergies tetanus antitoxin, and the other one down with sulfa drug allergies, so we have allergies or are allergic to penicillin should be used with caution or not. hydroxybutyrate ampicillin ampicillin penicillin derivatives, the chemical structure is similar to cross-allergy prone to these drugs were 0 lactam antibiotics for a claim, a total of p-lactam ring, which may be the basis of cross-allergic reactions. sulfa drugs,[link widoczny dla zalogowanych], tetanus antitoxin and amoxicillin chemical structure is different. may be a variety of allergic patients, this situation also known as multi-borne allergies. literature suggests that the impurities in the drug and the polymer produced at high temperature can also cause skin response, not entirely pure essential drugs, penicillin also have this cable as much as the original response to the difficulties. This was observed in 2 patients the drug is only served on the 2nd to skin rash, and some medication one week after the rash, the incidence of drug rash there is no obvious relationship between dose, according to data recorded in the incidence of drug eruption male to female ratio of 3:2. This sample also showed that males slightly higher than that involved women. Che data show that hydroxyl benzyl penicillin drug eruption occurring nitrogen with no significant relationship between age, skin damage occurred in parts of the trunk, limbs, and ampicillin rash caused by skin rash similar to group classification Feng Zhao identified by the typing method proposed classification, the number of lesions was too much like scarlet fever or measles-like type, small type for the purpura , polymorphic erythema-like,[link widoczny dla zalogowanych], urticaria-like, consistent with the literature.