mbt schoenen Perioperative use of antibiotics to p

lin06900 · Wysłany: Czw 8:33, 24 Mar 2011

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Perioperative use of antibiotics to prevent dry socket after tooth extraction in clinical research

Is the surgical removal of mandibular impacted wisdom teeth difficult, cuts hurt more 3. In this study, on both sides of the same patient under the collar points, respectively, were impacted wisdom tooth A, B group, C group of impacted teeth of the situation is broadly in line with A, I were comparable, neither Impacted and soft tissue impaction,[link widoczny dla zalogowanych], This makes surgery difficult roughly equal. In addition, as the treatments are quite technical proficiency, so reduce the trauma of the difference. 32 ways to prevent infection of the administration of the traditional method of negative 32.1 after a few days using the traditional method of continuous administration for prevention of postoperative wound infection is very prevalent,[link widoczny dla zalogowanych], but the effect is not ideal, but will increase even suggested that infections may l4J. The reason, partly because the doctors over-reliance on antibiotics, ignoring the concept of sterile and formal operation, the other hand, this approach was mainly due to improper administration time. Experimental proof of the bacterial contamination of the wound after 3 ~ 4h administration can not prevent infection, administration of traditional methods to achieve effective blood concentration over time are generally in 3h, it is difficult to prevent infection. 3.2.2 Perioperative administration of antibiotics,[link widoczny dla zalogowanych], the use of design principles to achieve the purpose of prevention of infection, then the wound during surgery has remained within the lowest effective concentration of antibiotics is the key to success. Perioperative administration of the timing of the design is based on this principle, namely, preoperative 30 - 60min to fold the amount of conventional antibiotics, the antibiotic concentration within the organization that is reached during operation of effective bactericidal or bacteriostatic concentration intraoperative administration depends on the length of surgery and drugs used to ask the length of the half-life. In this study, the operating time is generally within 2h, to the end station is half-life of drugs, so no additional administration of surgery, and after a strain of the wound was soaked, so in the early wound healing of continuous administration of 24h before to prevent postoperative wound contamination, causing infection and the occurrence of dry socket. The choice of drugs will be 3.3 cents security is a new broad-spectrum penicillin antibiotic, against Gram-positive cocci and gram-negative bacteria have a certain role in the killing, the effective rate of treatment of oral infections. Pharmacokinetic studies have shown that oral administration of 0.5g of the product to reach the peak time for 1h, and quickly distributed to body tissues, organs and body fluids, 6o% ~ 70% of drug excreted from the kidney to the prototype, half-life of 13h, these features The drug is suitable for prompt surgical extraction of perioperative use of drugs,[link widoczny dla zalogowanych], with high efficiency to achieve and maintain an effective plasma concentration time appropriate, easy to use, the advantages of fewer side effects. '3 .4 Two administration methods on prevention of dry socket comparison of the experimental results show that: The traditional method of using the security will be sen B, dry socket rate was 1321%, not the use of antibiotics C, dry socket Disease incidence was 24.59%, the two groups have a more obvious clinical significance, but no significant statistical significance (P> 0.05) of perioperative administration of A group, incidence of dry socket 3 .77%, and B, C group the two groups were statistically significant (P <0.05), this result speaks for itself in the traditional method of preventing the use of antibiotics for the socket on the basis of clinical effects, perioperative delivery method is more scientific and effective. Its scientific features: First, prevention of infection and prevention of dry socket with high success rate, with statistical significance; second, with other scholars to study the use of antibiotics to prevent perioperative infection in the incision was consistent; Third, Perioperative medication to reduce the amount of the drug to avoid drug resistance caused by the abuse and economic waste, a waste of time to ask.
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