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ORANGE EKSTRAKLASA
Dołączył: 03 Mar 2011
Posty: 720
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Ostrzeżeń: 0/5 Skąd: England
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Wysłany: Wto 17:07, 08 Mar 2011 |
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Amlodipine besylate in patients with essential hypertension Efficacy
Review indicators: 24h average systolic blood pressure (24hSBP) and diastolic blood pressure (24hDBP), daytime average systolic blood pressure (dSBP) and diastolic blood pressure (dDBP), nighttime systolic blood pressure (nSBP) and diastolic blood pressure (nD-BP); 24hHR change ( 24hHR). Administration methods: acid L-Amlodipine (brand name: Shi Hui Da, 2.5mg / film, Jilin Pharmaceutical Co.,[link widoczny dla zalogowanych], Ltd.-day wind products), the initial dose of 2.5mg / d,[link widoczny dla zalogowanych], 4 weeks up to target BP persons (sitting DBP 50. Adverse reactions: 4 cases, 1 case of dizziness, headache in 1 case,[link widoczny dla zalogowanych], mild lower extremity edema in 2 cases,[link widoczny dla zalogowanych], to continue taking all completed course of treatment. 3 Discussion amlodipine besylate is the third generation of dihydrotestosterone pyridine calcium channel blockers, and its elimination half-life of 35 ~ 50h, oral absorption of slow and safe, taking 1 per day to maintain an effective blood concentration of 24h, the role of durable constant. Our results show that: amlodipine besylate Buck T: P> 50, in patients with mild to moderate EH,[link widoczny dla zalogowanych], 1 day 24h 2.5 ~ 5.0mg effectively maintain the efficacy of the entire treatment period, smooth and continuous decline in BP, had no effect on the circadian rhythm.
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