Paclitaxel in the treatment of 67 cases of lung ca

e707004304 · Wysłany: Wto 12:56, 08 Mar 2011

Paclitaxel in the treatment of lung cancer care and clinical observation of 67 cases

Diameter) filter before infusion into the body. Nurse on duty visit should focus on patients undergoing chemotherapy. In this group of patients we observed, 2 patients lost in the liquid to 3 / 4 and 4 / 5, there are different degrees of throat itching, chest tightness, breathing accelerated to 26 - to 28 beats / min, looking flushing, blood pressure and other symptoms of an allergic reaction, including immediate replacement of the liquid drip infusion tube, to give low-flow oxygen inhalation, given intravenous injection of 10mg of dexamethasone and other anti-allergy treatment, patient comfort, and the patient with the doctor is watching close observation of the patient's bedside vital signs, l0 minutes later, the patient self-inductance of the symptoms improved, stable vital signs, 20 minutes later, the patient symptoms disappeared completely after 1 hour by a medical examination agreed, then the remaining liquid to a slow intravenous infusion l0 ~ l5 drops / min, l5 minutes, once a vital signs monitor, bedside observation of all the drugs in patients with end drops, no adverse reactions. The other patients with acute severe allergic reactions. Enter into the body lml solution of paclitaxel,[link widoczny dla zalogowanych], the patients with frequent cough, facial flushing, lips cyanosis, sweating, restlessness, blood pressure, abdominal pain, immediately replace the infusion bottle and infusion tube, oxygen, epinephrine Jing ling push, dexamethasone 10mg bolus, phenergan 25mg intramuscular injection, the symptoms were not relieved after 3 minutes, blood pressure dropped to 60/40 mm Hg, immediate boost drugs, a little relief of symptoms after 2 minutes. 8 minutes after the patient quiet, stable vital signs, symptoms disappeared after 30 minutes. L2-hour observation, the patient has been in the normal range of vital signs, and no other discomfort,[link widoczny dla zalogowanych], but serious allergic reaction, only to re-adjust the treatment. In fact, the patient once a month prior to the application of paclitaxel infusion was smooth, no special discomfort, which is the second application, the emergence of severe acute allergic reactions. Similar situations in order not to cause economic loss to patients, nurses and doctors in our department after consultation with the infusion method of the drug made a little adjustment. Each application of paclitaxel chemotherapy, first dissolved l / 5 of the dose for slow intravenous infusion, every 5 minutes as required, l5-minute monitoring of vital signs, I, 5 drops of the drug without adverse reaction completed, then the remaining average rate of drug infusion dissolved. Although severe allergic reactions if the patient adjust the treatment, the patient only the economic losses caused by small, two post-dose continuous infusion of total patients still amount to be applied, it had no effect on the treatment of patients. 3.3.1 3.3 after treatment care diet: gastrointestinal reaction induced by paclitaxel is not heavy, but the patient is combination therapy, most patients still have no appetite,[link widoczny dla zalogowanych], nausea, vomiting, etc., to provide guidance to patients like family the light, nutritious, avoid greasy, spicy foods, small meals often, pay attention to eating environment, eat dates, peanuts, white fungus. 3.3.2 activity tolerance: a sense of fatigue in patients, the guide its not to go out, getting enough rest and avoid fatigue. 3.3.3 Bone marrow suppression: to give rise white blood cells, platelets and red blood cell drug use. When necessary, direct component transfusion. Account of patients wash their hands, pay attention to food hygiene,[link widoczny dla zalogowanych], to prevent the flu who visits, strengthen oral skin and mucous membrane protection, self-observation without bleeding symptoms, such as: big, urine, sputum, skin and close observation of the body, severe bone marrow suppression, to give protective isolation. 3.3.4 joints, muscle pain: massage guide families, conditional to do physical therapy, oral wear fun and so on. 3.3.5 Hair loss: 15 to 20 days after chemotherapy, some patients will have varying degrees of hair loss, guiding patients can wear hats, wigs modification. Inform patients, hair loss is temporary, month later to re-grow, hair loss caused by the appearance of defects and short-term effective treatment of cancer is negligible in comparison. 4 discussed above, the effect of paclitaxel treatment of lung cancer is satisfactory,[link widoczny dla zalogowanych], but the standard anti-allergy treatment is the premise of safe medication Taxol. Drug monitoring of vital signs during the chemotherapy is paclitaxel security guarantees. Therefore, nurses need to side against the main characteristics of the work of strengthening the good care and close observation of vital signs to detect early symptoms of allergic reactions and timely treatment to prevent severe allergic reactions occur in order for the successful completion of chemotherapy in cancer patients, so that satisfaction of patients and their families, but also improve our quality of care.