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Silicosis total number of cells in bronchoalveolar lavage fluid in rats,[link widoczny dla zalogowanych], LDH,[link widoczny dla zalogowanych], protein ...
Compared with the infected dust plus days:. P <o. 05. days, no significant difference, but compared with the 90 days were significantly different and very significant (P <0.05 or P <0.01). Table 3, when the dust of different transfection experiment and control groups asked a large ~ BALF total Determination of protein content compared with the dye compared to the dust port 0 days:. P <0.05. O13 Discussion 3.1 Under normal circumstances, BALF cell composition and the composition of non-cellular components. When a lot of dust inhalation of the lungs, its cellular components and non-cellular components were significant changes in the old place, the number of alveolar macrophages in lymphocyte roar Vice Wedelia phase: neutrophils also increased significantly, they release hazardous substances and cell media points lead loss. Another Department of Near - even cells and tissues and form a complex network structure, mutual restraint, interaction and mutual promotion, leading to lung tissue damage and destruction of cells in this complex biological reaction in a key role in the onset of silicosis ; ¨. Vision surgery to wash out the use of BAL and non-cellular components of these cells, changes to alleviate or reduce the incidence of silicosis and development, will play a useful role. The experimental results showed that rats infected BALF of silicosis dust of time can wash out the large number of cells, the total number up to 58.81 × 10. . The experimental results and clinical side of the whole lung lavage in patients with silicosis or lung lavage that reported ¨ ¨. Reports based on experimental studies and clinical data point of view, the application can flush out a large number of BAL cells in patients. Expected to alleviate alveolar inflammation and ease the development of silicosis is beneficial change. BAL technique for the treatment of silicosis is also possible. 3.2LDH is a cytosolic enzyme, our results show that the dye dust 7,15,3 O, 9O days, LDH activity in BALF were higher, indicating alveolar space during collapse of a large number of cell destruction. The destruction of a large number of cells and the capillary basement membrane damage, a large number of protein accumulation in the alveolar space, causing protein PAP. The results showed that the determination of BALF, BAL Sin not only a large number of patients but also can wash out the cells a large number of proteins, suggesting that less than on reducing lung inflammation, lung damage reduction benefit, but also have a positive role in improving the symptoms. ¨ the literature reported that BAL patients. 207. Protein PAP and pulmonary results are consistent with pneumoconiosis. Thus application of BAL treatment of silicosis patients were not only reasonable but also possible. In summary, k3o days ago, compared with the dye dust 9O days. The total number of small roar, UH difference between activity and protein content have a 'significant irresolute = i. Students often a word meaning. Can be seen, the application BAL in the treatment of silicosis in the early or acute phase is appropriate. Nevertheless, the dye dust 9O three days described in the standard rat BALF was still significantly higher in control rats, and the difference was very significant (P <O.01). Prompted significant changes even in the silicosis cases, BAL technique can still wash out the product of a large number of cells and their destruction, which is about a new light and other reports, Tuochen 21 - '30 years later by BAL silicosis still washed out a large number of patients with cells and silica dust is also consistent. Therefore, the BAL technique that also applies in patients with advanced silicosis.
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