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Wysłany: Śro 14:08, 16 Mar 2011 |
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Helicobacter pylori infection and iron deficiency anemia complicated clinical observation
12 weeks, hemoglobin (IIb), serum iron (SI), ferritin (sF). 2 results of diagnostic endoscopy 1O cases of chronic superficial gastritis. 8 cases of chronic atrophic gastritis, gastric inflammation in 15 cases, 7 cases of gastric ulcer, duodenal ulcer 2O cases. A group of patients treated for 4 weeks 1O Hb rose to normal. After 12 weeks,[link widoczny dla zalogowanych], 34 patients with Hb rose to normal and slightly elevated Hb in 4 cases, 2 cases with Hb decreased bleeding again. 4 cases of group B after 4 weeks of treatment Hb rose to normal,[link widoczny dla zalogowanych], 13 slightly increased after 12 weeks. Before and after treatment no significant difference. Anti-Hp therapy with the clothes iron for 4 weeks, 12 weeks Hb,[link widoczny dla zalogowanych], SI, sF were significantly increased. The difference between before and after treatment was significant. And pure iron 3 indicators before and after treatment did not change significantly. A group of therapeutic efficacy was 95% (38/40),[link widoczny dla zalogowanych], B group treatment efficiency of 20% (4 / 20),[link widoczny dla zalogowanych], the difference was highly significant (P <O.01). Table 1.3 Hp infection is the discussion of chronic gastritis, peptic ulcer, gastric cancer, gastric mucosa associated lymphoid tissue lymphoma of the major causes. Hp infection is conducive to radical cure gastritis, gastric ulcer. Study found that foreign scholars in recent years, with a variety of non-Hp-related gastrointestinal diseases and found that Hp infection can also result in iron deficiency and malnutrition in humans, the key factors leading to IDA, is part of the IDA were the main reason for poor efficacy of repeated iron 12l. Table 1 The two groups were compared before and after treatment index of each test (F ~ s) Note: The comparison between groups P <0.05: A set of before and after treatment P <0.01: B 0.05 compared before and after treatment. IDA on the basis of clinical causes, symptoms, signs and laboratory tests to make diagnosis easier. Important to find the cause of iron deficiency. It has been reported, Hp-positive women of childbearing age in Hp-negative IDA incidence populations, suggesting that Hp and the IDA has some relevance. Anti-Hp therapy can increase iron absorption. Conducive to the increase of Hb ridicule. We 4O Hp-positive patients with iron while providing anti-Hp therapy. 12 weeks, 36 patients with hemoglobin increased to normal. Without at the same time anti-Hp Hp-positive patients treated 2O cases after 12 weeks of iron supplementation increases hemoglobin is not obvious. The difference between the two groups was significant. Detection of two groups of serum iron, ferritin, anti-Hp group also significantly increased anti-Hp therapy can explain to promote iron absorption or conducive to the use of iron absorption. Pathogenesis of iron absorption has not been fully elucidated. Hp may be located in the gastric mucosa, the massive proliferation of the gastric pH after breeding changes to reduce gastric acid secretion, decrease in serum iron, serum transferrin consumption, Hp has a number of genes encoding iron uptake can hinder the absorption of iron protein, bacteria compete for food with the body's iron, increased iron needs D1. 20 cases without anti-Hp therapy after 12 weeks of iron supplementation increased Hb slowly, it may be necessary to complement Hp after iron saturation. The body can absorb some of that increase in some patients with Hb, serum iron, ferritin also increased that the two cases rose to normal, but most patients with poor body absorb iron. Hb rose slowly or increased. So. Clinically, a variety of chronic diseases caused by the exclusion of IDA, iron treatment efficacy was not obvious, consider the detection of Hp infection and anti-Hp therapy. Especially those with chronic gastritis, iron at the same time anti-Hp treatment, in order to facilitate the use of iron absorption, increased iron effect.
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