Endotoxin-induced acute lung injury early gene exp

e707004304 · Wysłany: Sob 12:51, 12 Mar 2011

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Endotoxin-induced early gene expression profile of acute lung injury in mice

Twist 3 to 4 weeks after the crutch ambulation functional exercise, 3 months after the next single, minimally invasive, reliable fixation, results were satisfactory. To non-weight-bearing walking. Key words: Femoral neck fracture; reset; cannulated screws; fixation Key words: R683.42 Document code: B common femoral neck fracture is a fracture in the elderly, one prone to femoral head necrosis and nonunion. From 2000 to 2007, the author hollow screw with closed reduction and internal fixation of femoral neck fracture in 78 cases, achieved good results, reported as follows. 1 General information The clinical data of 78 cases,[link widoczny dla zalogowanych], male 46, female 32 cases; aged 18-79 years, mean 61.5 years old. 40 cases of femoral neck fracture on the left and right in 38 cases. The causes of injury: falls 58 cases, 20 cases of road traffic injuries. Injury to the hospital for 2 hours to 10 days. Classified according to fracture site: 14 cases under the head, the neck-type 38 cases, 26 cases of basal-type. According to Garden classification: Ⅱ type 20 cases, Ⅲ type 46 cases,[link widoczny dla zalogowanych], Ⅳ type l2 cases. Combined medical disease in 15 patients preoperatively after 3-5 days of medical treatment. 2 treatments were performed after admission limb tibial tubercle skin traction or skeletal traction, traction time is 3-7 days. Surgery using continuous epidural anesthesia, the patient supine on the traction bed orthopedic surgery, limb outreach 30. ,[link widoczny dla zalogowanych], Internal rotation 15. Proper traction. Patients who left posterolateral internal rotation in the pulling up his right groin at the same time press down on the head, you can make fracture reduction. C-arm x-ray machine perspective confirmed fractures of the position well, normal neck shaft angle, closed reduction successful. Routine disinfection, shop towels, in the upper thigh lateral tuberosity mainly as a 5-6cm long vertical incision to expose the cortical bone, the greater trochanter to the femoral head 3 ~ 4cm under the direction parallel to the longitudinal axis of the femoral neck drill 1 gold guide pin, guide pin position to know whether the picture perfect, and then in a guide pin parallel to drill into the top of the first guide wire pieces 2,3, the three guide pins on the lateral view as an inverted Photo confirmed fractures of the bit and guide pin in good position, the tip from the femoral head cartilage surface of about 0.5 ~ 1cm, select the appropriate length of guide wire according to the hollow screw, and then tapping the direction along the guide pin, screw into the screw. Pull out the guide pin, flush sutures Received 2007-01-08; Revised :2007 -03-283 Results Of the 78 cases were followed up for l0 ~ 36 months, an average of 20 months. Fracture healing: healing in 70 cases, nonunion in 6 cases, 2 cases of femoral head necrosis (all Garden1V fracture). Functional evaluation according to Harris scoring excellent in 48 cases, good in 20 cases, 7 cases, poor in 3 cases; good rate of 87.2%. Discuss the key to the treatment of femoral neck fracture is to restore function and reduce hip fracture, the incidence of femoral head necrosis. Advantages of this method: (1) trauma, no incision of the joint capsule, not exposed fracture of the femoral head blood flow of small; (2) early mobilization after surgery can avoid the complications caused by long-term bed rest such as pressure ulcers, hypostatic pneumonia, urinary tract infections, cardiovascular and cerebrovascular embolism, quick recovery of function; (3) three screws in the femoral neck in an inverted to prevent the varus deformity and shortening ...; (4) surgery is simple, safe, less bleeding, especially for people with severe systemic disease can not tolerate other larger surgery; (5) the material is titanium, good histocompatibility, less rejection, and no effect on CT, MRI, can be carried for life. Note: (1) good reduction is the key to successful treatment, patients should strive for anatomic reduction or basic anatomical reduction; (2) Note that choosing a needle entry point and direction, to avoid penetrating the joints, the tip from the femoral head should be cartilage about 0.5-1cm; (3) after surgery to achieve the to understand the fracture healing, fracture lines disappeared, before being gradually load; (5) femoral neck fractures, especially GardenIV fracture, due to greater destruction of the femoral head blood supply, nonunion, and femoral head necrosis higher rate of fractures, especially for this age of> 65 patients, conditions permitting, the preferred hemiarthroplasty or total hip arthroplasty.