Aminophylline 114 cases of adverse drug reactions

e707004304 · Wysłany: Pon 23:23, 21 Mar 2011

Aminophylline 114 cases of adverse drug reactions

Adverse events occurred original Ma (This article had 114 cases of adverse reactions are normal operation, 89 cases occurred ). This, in the administration set the course and speed to control the dose and at any time monitor the situation. 3.3 Relationship with the administration method of 114 cases of adverse reactions in this oral administration of 22 cases ,[link widoczny dla zalogowanych], 92 cases of intravenous administration , intravenous administration can be seen more susceptible to adverse reactions , it is difficult to control the rate of intravenous plasma concentration led to the rapid }: l . 3.4 Relationship with this combination a total of 18 cases of adverse reactions is irrational combination . L5 cases where cimetidine , ciprofloxacin , 1 case 1 case of ofloxacin , smoke hydrazine in 1. Data indicate that cimetidine can reduce theophylline clearance string ,[link widoczny dla zalogowanych], metabolism was inhibited , making it 2-3 times higher blood concentration , t. . By 60 %, m is easy to toxicity . Isoniazid , quinolones are all liver microsomal oxidase inhibitor , to slow down the metabolism of wing base , resulting in accumulation of poisoning. The other parts can increase the toxicity of drugs aminophylline also chloramphenicol , erythromycin, lincomycin , verapamil and so on. The aminophylline in a patient taking theophylline should be avoided to increase the toxicity of combination therapy. If necessary MS, should be considered appropriate to reduce the dose of aminophylline . 4 Conclusion As in the clinical application of aminophylline in patients with different pathophysiological conditions ,[link widoczny dla zalogowanych], large individual differences , together with its therapeutic index is small, due to adverse reactions involving multiple body organ systems , including the most common response to the cardiovascular system , clinical The performance of very complex and diverse . This proposal Shuai Yue , retaining ten leaf 1 in the clinical use of drugs I must be careful , it is best able to do individual medication,[link widoczny dla zalogowanych], dosage and strict system of screw speed and conditions should make blood concentration monitoring . And to avoid unreasonable combination therapy. And do not strengthen nursing observation,[link widoczny dla zalogowanych], close monitoring of patients during treatment I clinical response , especially for elderly patients and even more so . If any abnormal situation should be promptly discontinued and appropriate symptomatic treatment carried out in order to avoid greater damage .