Dual role of antimicrobial agents _1783

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Dual role of antimicrobial agents

System, MICo ≤ 0.06 in a l ~ g / m!. Staphylococcus, streptococcus, the card he bacteria, Corynebacterium, influenza bacillus, Li Jin te bacteria and Neisseria lactamase enzymes producing methicillin-resistant iron-deficiency anemia golden New Research Trends (continued ) 3. Reflect the iron status and infection immunity in the serum transferrin (transferrin) have made agents or inhibit the activity of fungi, and have known to inhibit bacterial and fungal growth. Many studies report that on such non-specific anti-infective factors, especially in children, nutritional status is crucial, however, not much here for discussion. On the one hand, when the body prone to infections of iron deficiency, which is a lot of people are aware of the fact that, while there are many reports that patients given the state of iron deficiency Ji infection tends to decrease after treatment was also confirmed. Iron deficiency as the previous change in terms of clinical biochemistry as spoken, iron as heme proteins or denatured proteins constitute a wide variety of enzyme flavin substrate, the time when the iron deficiency will result in the amount of these enzymes and abnormal mass, resulting in the synthesis of DNA within the cell caused by inhibition and abnormal lymphocytes mitochondria and so on. On the other hand, when the state of iron deficiency in the body, easily lead to infection of another skin disease called chronic candidiasis of mucous immune deficiency syndrome, the disease is mainly the function of epithelial barrier occurs. In the deficiency state, on the humoral immunity issue,[link widoczny dla zalogowanych], there are reports that there is no special exception, confirmed by the results of animal experiments, antibody production is suppressed. In addition, when other nutritional deficiencies, iron deficiency status will also appear, serum IgG is also reduced. In the deficiency state, on the cells of the immune capacity, reports that the study bacteria disease, the phenomenon of inhibition of naive lymphocytes, peripheral blood lymphocytes in a reduction of T, for a variety of antigens, reduced lymphocyte response, macrophage migration inhibitory factor decrease and so on. Why T ~ cells will reduce the still unclear, in short, due to be given iron treatment, iron status can be improved, those abnormal immune cells can be restored relatively quickly. Iron deficiency anemia has recently attracted attention because of Staphylococcus Dengjun sensitive. Pseudomonas aeruginosa, Enterococcus and Bacillus fragilis is less sensitive (MICno ≥ 30g/mI). The general lines of the i002, the drug ≤ 16 female / mI inhibited 97% of the isolates, cefotaxime a carboxymethyl oxime (CAZ) inhibited 9O, and cephalosporin oxygen prazosin (CPZ) inhibited 92, and can be bactericidal, the size of inoculum not affected, the anti-quinolone-or anti cAz strain often effective. BeskidG such as the Ro23-9424 in comparison with other cephalosporins, amikacin (Amikacin) of MIC break points as 1000 ~ g / m】. It seems the drug metabolism in the body FRX not many, not the main elimination pathway. This set of cephalosporin and quinolone antimicrobial agents in a dual appears to be promising. Additional clinical trials will provide information to make a real evaluation.